Use of the retinal vessel analyzer in ocular blood flow research

被引:203
作者
Garhofer, Gerhard [1 ]
Bek, Toke [2 ]
Boehm, Andreas G. [3 ]
Gherghel, Doina [10 ]
Grunwald, Juan [4 ]
Jeppesen, Peter [2 ]
Kergoat, Helene [5 ]
Kotliar, Konstantin [6 ]
Lanzl, Ines [6 ]
Lovasik, John V. [5 ]
Nagel, Edgar
Vilser, Walthard [7 ]
Orgul, Selim [8 ]
Schmetterer, Leopold [1 ,9 ]
机构
[1] Med Univ Vienna, Dept Clin Pharmacol, A-1090 Vienna, Austria
[2] Arhus Univ Hosp, Dept Ophthalmol, Aarhus, Denmark
[3] Univ Dresden, Dept Ophthalmol, Dresden, Germany
[4] Univ Penn, Sch Med, Dept Ophthalmol, Philadelphia, PA 19104 USA
[5] Univ Montreal, Sch Optometry, Montreal, PQ, Canada
[6] Tech Univ Munich, Dept Ophthalmol, Munich, Germany
[7] Imedos GmbH, Jena, Germany
[8] Univ Eye Clin, Basel, Switzerland
[9] Med Univ Vienna, Ctr Biomed Engn & Phys, A-1090 Vienna, Austria
[10] Aston Univ, Ophthalm Res Grp, Sch Life & Hlth Sci, Birmingham B4 7ET, W Midlands, England
关键词
ocular blood flow; physiology; reproducibility; retina; retinal vessel analyzer; standardization; PROLIFERATIVE DIABETIC-RETINOPATHY; ATHEROSCLEROSIS RISK; HYPEROXIA; DIAMETER; COMMUNITIES; ARTERIOLAR; CALIBER;
D O I
10.1111/j.1755-3768.2009.01587.x
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
The present article describes a standard instrument for the continuous online determination of retinal vessel diameters, the commercially available retinal vessel analyzer. This report is intended to provide informed guidelines for measuring ocular blood flow with this system. The report describes the principles underlying the method and the instruments currently available, and discusses clinical protocol and the specific parameters measured by the system. Unresolved questions and the possible limitations of the technique are also discussed.
引用
收藏
页码:717 / 722
页数:6
相关论文
共 22 条
[1]   Effect of different levels of hyperoxia on breathing in healthy subjects [J].
Becker, HF ;
Polo, O ;
McNamara, SG ;
BerthonJones, M ;
Sullivan, CE .
JOURNAL OF APPLIED PHYSIOLOGY, 1996, 81 (04) :1683-1690
[2]   Comparison of different hyperoxic paradigms to induce vasoconstriction: Implications for the investigation of retinal vascular reactivity [J].
Gilmore, ED ;
Hudson, C ;
Venkataraman, ST ;
Preiss, D ;
Fisher, J .
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2004, 45 (09) :3207-3212
[3]  
GRUNWALD JE, 1989, OPHTHALMOLOGY, V96, P1518
[4]  
GRUNWALD JE, 1984, OPHTHALMOLOGY, V91, P1447
[5]   Role of nitric oxide in regulation of retinal blood flow in response to hyperoxia in cats [J].
Izumi, Naohiro ;
Nagaoka, Taiji ;
Sato, Eiichi ;
Sogawa, Kenji ;
Kagokawa, Hiroyuki ;
Takahashi, Atsushi ;
Kawahara, Atsushi ;
Yoshida, Akitoshi .
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2008, 49 (10) :4595-4603
[6]   Systemic hyperoxia and retinal vasomotor responses [J].
Jean-Louis, S ;
Lovasik, JV ;
Kergoat, H .
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2005, 46 (05) :1714-1720
[7]   Retinal blood flow during hyperoxia in humans revisited: Concerted results using different measurement techniques [J].
Kiss, B ;
Polska, E ;
Dorner, G ;
Polak, K ;
Findl, O ;
Mayrl, GF ;
Eichler, HG ;
Wolzt, M ;
Schmetterer, L .
MICROVASCULAR RESEARCH, 2002, 64 (01) :75-85
[8]   Retinal vascular caliber in persons with type 2 diabetes - The Wisconsin epidemiological study of diabetic retinopathy: XX [J].
Klein, Ronald ;
Klein, Barbara E. K. ;
Moss, Scot E. ;
Wong, Tien Y. ;
Sharrett, A. Richey .
OPHTHALMOLOGY, 2006, 113 (09) :1488-1498
[9]   Relative importance of systemic determinants of retinal arteriolar and venular caliber [J].
Liew, Gerald ;
Sharrett, A. Richey ;
Wang, Jie Jin ;
Klein, Ronald ;
Klein, Barbara E. K. ;
Mitchell, Paul ;
Wong, Tien Y. .
ARCHIVES OF OPHTHALMOLOGY, 2008, 126 (10) :1404-1410
[10]   Variance of retinal vessel diameter response to flicker light. A methodical clinical study [J].
Nagel, E ;
Vilser, W ;
Fink, A ;
Riemer, T .
OPHTHALMOLOGE, 2006, 103 (02) :114-119