The aim of this study was to evaluate the effect of bronchial asthma on quality of life and sexual functioning of women. The study was conducted in a population of 72 women aged 18-45 (31 women treated for bronchial asthma and 41 healthy women). A specific questionnaire with a Polish version of Short Form-36 and Female Sexual Function Index was used as a research tool in this study. We found that the quality of life parameters for women with asthma were lower than for the controls in the following aspects: limitations due to physical health, limitations due to emotional problems, social functioning, energy/fatigue and emotional well-being. Asthmatic women showed worse sexual functioning in sexual arousal, lubrication, orgasm, sexual satisfaction, and pain domain. Sexual dysfunctions were diagnosed in 25.8% of asthmatic women and 17.1% of controls (P>0.05). In conclusion, bronchial asthma decreases quality of life and sexual functioning among women.