Pd(II)-Catalyzed Synthesis of Benzyl Benzoates via Benzyl C(sp3)-H Activation

被引：3
|
作者：
Duanmu, Dandan [1 ]
Leong, Pak-kin [1 ]
Jiang, Qibai [2 ]
Yan, Hong [1 ]
机构：
[1] Nanjing Univ, Sch Chem & Chem Engn, State Key Lab Coordinat Chem, Nanjing 210093, Jiangsu, Peoples R China
[2] Jiangsu Yangnong Chem Co Ltd, Yangzhou 225009, Jiangsu, Peoples R China
来源：
CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2017年 / 37卷 / 10期
基金：
中国国家自然科学基金;
关键词：
Pd(II)-catalysis; C-H activation; benzyl benzoates; perester; C-H ACTIVATION; INTRAMOLECULAR ALKANE ARYLATION; CATALYZED ALLYLIC OXIDATION; CROSS-COUPLING REACTIONS; BOND FUNCTIONALIZATION; CARBOXYLIC-ACIDS; CARBONYLATION; ALKYLATION; CLEAVAGE; ESTERS;
D O I：
10.6023/cjoc201704040
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient Pd(II)-catalyzed synthesis of benzyl benzoates via direct functionalization of benzyl C(sp(3))-H bonds was developed. The method features a broad substrate scope. This method features high tolerance of functional groups, mild reaction condition, and high chemoselective when there are multiple active C(sp(3))-H bonds. A plausible oxidative coupling mechanism was proposed on the basis of mechanistic studies.
引用
收藏
页码：2669 / 2677
页数：9
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