Downgrading BIRADS 3 to BIRADS 2 category using a computer-aided microcalcification analysis and risk assessment system for early breast cancer

被引：6
作者：
Giannakopoulou, Georgia [1 ,2 ]
Spyrou, George M. [3 ,4 ]
Antaraki, Argyro [3 ]
Andreadis, Ioannis [3 ,6 ]
Koulocheri, Dimitra [1 ,2 ]
Zagouri, Flora [1 ]
Nonni, Afroditi [5 ]
Filippakis, George M. [1 ]
Nikita, Konstantina S. [6 ]
Ligomenides, Panos A. [3 ]
Zografos, George C. [1 ]
机构：
[1] Univ Athens, Sch Med, Hippokratio Hosp, Breast Unit,Dept Propaedeut Surg 1, GR-11527 Athens, Greece
[2] Hippokrateion Hosp, Dept Radiol, Athens 11527, Greece
[3] Acad Athens, Informat Lab, Athens 11527, Greece
[4] Acad Athens, Biomed Informat Unit, Biomed Res Fdn, Athens 11527, Greece
[5] Univ Athens, Sch Med, Dept Pathol, GR-11527 Athens, Greece
[6] Natl Tech Univ Athens, Dept Elect & Comp Engn, Athens 15780, Greece
来源：
COMPUTERS IN BIOLOGY AND MEDICINE | 2010年 / 40卷 / 11-12期
关键词：
Early breast cancer; Microcalcifications; BIRADS; 3; CAD system; SVABB; MAMMOGRAPHIC MICROCALCIFICATIONS; CLUSTERED MICROCALCIFICATIONS; SCREENING MAMMOGRAPHY; DIAGNOSIS SCHEME; APPROPRIATE ROLE; BENIGN; BIOPSY; CLASSIFICATION; CARCINOMA; SEGMENTATION;
D O I：
10.1016/j.compbiomed.2010.09.005
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
This paper explores the potential of a computer-aided diagnosis system to discriminate the real benign microcalcifications among a specific subset of 109 patients with BIRADS 3 mammograms who had undergone biopsy, thus making it possible to downgrade them to BIRADS 2 category. The system detected and quantified critical features of microcalcifications and classified them on a risk percentage scale for malignancy. The system successfully detected all cancers. Nevertheless, it suggested biopsy for 11/15 atypical lesions. Finally, the system characterized as definitely benign (BIRADS 2) 29/88 benign lesions, previously assigned to BIRADS 3. and thus achieved a reduction of 33% in unnecessary biopsies. (C) 2010 Elsevier Ltd. All rights reserved.
引用
收藏
页码：853 / 859
页数：7
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