Extramedullary Orbital Granulocytic Sarcoma Without Bone Marrow Involvement: A Report of Two Cases

被引：4

作者：

Isik, Pamir ^{[1
]}

Tavil, Betul ^{[1
]}

Tunc, Bahattin ^{[1
]}

Yarali, Nese ^{[1
]}

Demir, Ahmet ^{[1
]}

Cetin, Mualla ^{[2
]}

机构：

[1] Ankara Childrens Hematol & Oncol Hosp, Dept Pediat Hematol, TR-06110 Ankara, Turkey

[2] Hacettepe Univ, Fac Med, Pediat Hematol Unit, TR-06100 Ankara, Turkey

来源：

PEDIATRIC HEMATOLOGY AND ONCOLOGY | 2011年 / 28卷 / 01期

关键词：

acute myeloid leukemia; children; granulocytic sarcoma; HIGH-DOSE METHYLPREDNISOLONE; ACUTE MYELOBLASTIC-LEUKEMIA; ACUTE MYELOID-LEUKEMIA; INITIAL MANIFESTATION; TURKISH CHILDREN; TUMOR; REMISSION; SURVIVAL; CHLOROMA;

D O I：

10.3109/08880018.2010.511439

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The authors present herein 2 extramedullary orbital granulocytic sarcoma (GS) cases without bone marrow involvement in view of their rarity and also to reevaluate the treatment approach in this disease. Seven days of high-dose methyl prednisolone (HDMP) treatment (3 days 30 mg/kg/day and 4 days 20 mg/kg/day) was administered initially, and subsequently Acute Myeloid Leukaemia-Berlin Frankfurt Munster (AML-BFM) 2004 treatment protocol was continued for 2 cases. Eye findings of the cases resolved considerably with HDMP treatment. They have still been under systemic chemotherapy without any complication for 1 year. Thus, early diagnosis and AML-targeted intensive chemotherapy improve the prognosis of GS even if there is no bone marrow involvement.

引用

页码：65 / 70

页数：6

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