Extramedullary Orbital Granulocytic Sarcoma Without Bone Marrow Involvement: A Report of Two Cases

被引：4
作者：
Isik, Pamir [1 ]
Tavil, Betul [1 ]
Tunc, Bahattin [1 ]
Yarali, Nese [1 ]
Demir, Ahmet [1 ]
Cetin, Mualla [2 ]
机构：
[1] Ankara Childrens Hematol & Oncol Hosp, Dept Pediat Hematol, TR-06110 Ankara, Turkey
[2] Hacettepe Univ, Fac Med, Pediat Hematol Unit, TR-06100 Ankara, Turkey
来源：
PEDIATRIC HEMATOLOGY AND ONCOLOGY | 2011年 / 28卷 / 01期
关键词：
acute myeloid leukemia; children; granulocytic sarcoma; HIGH-DOSE METHYLPREDNISOLONE; ACUTE MYELOBLASTIC-LEUKEMIA; ACUTE MYELOID-LEUKEMIA; INITIAL MANIFESTATION; TURKISH CHILDREN; TUMOR; REMISSION; SURVIVAL; CHLOROMA;
D O I：
10.3109/08880018.2010.511439
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The authors present herein 2 extramedullary orbital granulocytic sarcoma (GS) cases without bone marrow involvement in view of their rarity and also to reevaluate the treatment approach in this disease. Seven days of high-dose methyl prednisolone (HDMP) treatment (3 days 30 mg/kg/day and 4 days 20 mg/kg/day) was administered initially, and subsequently Acute Myeloid Leukaemia-Berlin Frankfurt Munster (AML-BFM) 2004 treatment protocol was continued for 2 cases. Eye findings of the cases resolved considerably with HDMP treatment. They have still been under systemic chemotherapy without any complication for 1 year. Thus, early diagnosis and AML-targeted intensive chemotherapy improve the prognosis of GS even if there is no bone marrow involvement.
引用
收藏
页码：65 / 70
页数：6
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