nNOS uncoupling by oxidized LDL: Implications in atherosclerosis

被引：8
作者：
Navia-Pelaez, Juliana Maria [1 ]
Campos-Mota, Gianne Paul [1 ]
Araujo de Souza, Jessica Cristina [1 ]
Aguilar, Edenil Costa [1 ,2 ]
Stergiopulos, Nikos [3 ]
Alvarez-Leite, Jacqueline Isaura [2 ]
Aggum Capettini, Luciano Santos [1 ]
机构：
[1] Univ Fed Minas Gerais, Inst Biol Sci, Dept Pharmacol, Lab Vasc Biol, Av Antonio Carlos 6627, BR-31270901 Belo Horizonte, MG, Brazil
[2] Univ Fed Minas Gerais, Inst Biol Sci, Dept Biochem & Immunol, Lab Atherosclerosis & Nutr Biochem, Av Antonio Carlos 6627, BR-31270901 Belo Horizonte, MG, Brazil
[3] Ecole Polytech Fed Lausanne, Inst Bioengn, Lab Hemodynam & Cardiovasc Technol, BM 5128 Stn 17, CH-1015 Lausanne, Switzerland
来源：
FREE RADICAL BIOLOGY AND MEDICINE | 2017年 / 113卷
关键词：
NITRIC-OXIDE SYNTHASE; LOW-DENSITY-LIPOPROTEIN; NF-KAPPA-B; FACTOR ACTIVATOR PROTEIN-1; ENDOTHELIAL-CELLS; HYDROGEN-PEROXIDE; OXIDATIVE STRESS; GENE-EXPRESSION; RENAL-FUNCTION; KNOCKOUT MICE;
D O I：
10.1016/j.freeradbiomed.2017.09.018
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
[No abstract available]
引用
收藏
页码：335 / 346
页数：12
相关论文
共 50 条
[1]   OXIDIZED LDL INDUCES TRANSCRIPTION FACTOR ACTIVATOR PROTEIN-1 BUT INHIBITS ACTIVATION OF NUCLEAR FACTOR-KAPPA-B IN HUMAN VASCULAR SMOOTH-MUSCLE CELLS [J].
ARES, MPS ;
KALLIN, B ;
ERIKSSON, P ;
NILSSON, J .
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 1995, 15 (10) :1584-1590
[2]   NOS1-derived nitric oxide promotes NF-κB transcriptional activity through inhibition of suppressor of cytokine signaling-1 [J].
Baig, Mirza Saqib ;
Zaichick, Sofia V. ;
Mao, Mao ;
de Abreu, Andre L. ;
Bakhshi, Farnaz R. ;
Hart, Peter C. ;
Saqib, Uzma ;
Deng, Jing ;
Chatterjee, Saurabh ;
Block, Michelle L. ;
Vogel, Stephen M. ;
Malik, Asrar B. ;
Consolaro, Marcia E. L. ;
Christman, John W. ;
Minshall, Richard D. ;
Gantner, Benjamin N. ;
Bonini, Marcelo G. .
JOURNAL OF EXPERIMENTAL MEDICINE, 2015, 212 (10) :1725-1738
[3]  
Campos-Mota G. P., 2016, ATHEROSCLEROSIS
[4]   Decreased production of neuronal NOS-derived hydrogen peroxide contributes to endothelial dysfunction in atherosclerosis [J].
Capettini, L. S. A. ;
Cortes, S. F. ;
Silva, J. F. ;
Alvarez-Leite, J. I. ;
Lemos, V. S. .
BRITISH JOURNAL OF PHARMACOLOGY, 2011, 164 (06) :1738-1748
[5]   Neuronal nitric oxide synthase-derived hydrogen peroxide is a major endothelium-dependent relaxing factor [J].
Capettini, L. S. A. ;
Cortes, S. F. ;
Gomes, M. A. ;
Silva, G. A. B. ;
Pesquero, J. L. ;
Lopes, M. J. ;
Teixeira, M. M. ;
Lemos, V. S. .
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2008, 295 (06) :H2503-H2511
[6]   Relative contribution of eNOS and nNOS to endothelium-dependent vasodilation in the mouse aorta [J].
Capettini, Luciano S. A. ;
Cortes, Steyner F. ;
Lemos, Virginia S. .
EUROPEAN JOURNAL OF PHARMACOLOGY, 2010, 643 (2-3) :260-266
[7]   Role of nNOS in regulation of renal function in hypertensive Ren-2 transgenic rats [J].
Cervenka, L ;
Kramer, HJ ;
Maly, J ;
Vanecková, I ;
Bäcker, A ;
Bokemeyer, D ;
Bader, M ;
Ganten, D ;
Mitchell, KD .
PHYSIOLOGICAL RESEARCH, 2002, 51 (06) :571-580
[8]   Role of nNOS in regulation of renal function in angiotensin II-induced hypertension [J].
Cervenka, L ;
Kramer, HJ ;
Maly, J ;
Heller, J .
HYPERTENSION, 2001, 38 (02) :280-285
[9]  
Chavakis E, 2001, CIRCULATION, V103, P2102
[10]  
Chen L, 1997, J LIPID RES, V38, P546
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