ANTHEPROT:: An integrated protein sequence analysis software with client/server capabilities

被引:123
作者
Deléage, G [1 ]
Combet, C [1 ]
Blanchet, C [1 ]
Geourjon, C [1 ]
机构
[1] Inst Biol & Chim Prot, CNRS UMR 5086 Bioinformat & RMN Struct, Pole Bioinformat Lyonnais, F-69367 Lyon 07, France
关键词
protein sequence analysis; multiple alignment; secondary structure prediction; Web server;
D O I
10.1016/S0010-4825(01)00008-7
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Programs devoted to the analysis of protein sequences exist either as stand-alone programs or as Web servers. However, stand-alone programs can hardly accommodate for the analysis that involves comparisons on databanks, which require regular updates. Moreover, Web servers cannot be as efficient as stand-alone programs when dealing with real-time graphic display. We describe here a stand-atone software program called ANTHEPROT, which is intended to perform protein sequence analysis with a high integration level and clients/server capabilities. It is an interactive program with a graphical user interface that allows handling of protein sequence and data in a very interactive and convenient manner. It provides many methods and tools, which are integrated into a graphical user interface. ANTHEPROT is available for Windows-based systems. It is able to connect to a Web server in order to perform large-scale sequence comparison on up-to-date databanks. ANTHEPROT is freely available to academic users and may be download at http://pbil.ibcp.fr/ANTHEPROT. (C) 2001 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:259 / 267
页数:9
相关论文
共 24 条
[1]   Gapped BLAST and PSI-BLAST: a new generation of protein database search programs [J].
Altschul, SF ;
Madden, TL ;
Schaffer, AA ;
Zhang, JH ;
Zhang, Z ;
Miller, W ;
Lipman, DJ .
NUCLEIC ACIDS RESEARCH, 1997, 25 (17) :3389-3402
[2]   The PROSITE database, its status in 1995 [J].
Bairoch, A ;
Bucher, P ;
Hofmann, K .
NUCLEIC ACIDS RESEARCH, 1996, 24 (01) :189-196
[3]  
Boger J, 1986, 6 INT C IMM TOR, P250
[4]   NPS@:: Network Protein Sequence Analysis [J].
Combet, C ;
Blanchet, C ;
Geourjon, C ;
Deléage, G .
TRENDS IN BIOCHEMICAL SCIENCES, 2000, 25 (03) :147-150
[5]   MULTIPLE SEQUENCE ALIGNMENT WITH HIERARCHICAL-CLUSTERING [J].
CORPET, F .
NUCLEIC ACIDS RESEARCH, 1988, 16 (22) :10881-10890
[6]   AN ALGORITHM FOR PROTEIN SECONDARY STRUCTURE PREDICTION BASED ON CLASS PREDICTION [J].
DELEAGE, G ;
ROUX, B .
PROTEIN ENGINEERING, 1987, 1 (04) :289-294
[7]  
DELEAGE G, 1988, COMPUT APPL BIOSCI, V4, P351
[8]  
Frolov AS, 1997, COMPUT APPL BIOSCI, V13, P243
[9]  
Galtier N, 1996, COMPUT APPL BIOSCI, V12, P543
[10]   ANALYSIS OF ACCURACY AND IMPLICATIONS OF SIMPLE METHODS FOR PREDICTING SECONDARY STRUCTURE OF GLOBULAR PROTEINS [J].
GARNIER, J ;
OSGUTHORPE, DJ ;
ROBSON, B .
JOURNAL OF MOLECULAR BIOLOGY, 1978, 120 (01) :97-120