Prevalence and clinical profile of troponin T mutations among patients with hypertrophic cardiomyopathy in Tuscany

被引：27

作者：

Torricelli, F

Girolami, F

Olivotto, I

Passerini, I

Frusconi, S

Vargiu, D

Richard, P

Cecchi, F

机构：

[1] Azienda Osped Careggi, UO Citogenet & Genet, Cytogenet & Genet Unit, I-50134 Florence, Italy

[2] Azienda Osped Careggi, Reg Referral Ctr Myocardial Dis, I-50134 Florence, Italy

[3] Hop La Pitie Salpetriere, Cardiogenet Unit, Paris, France

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 2003年 / 92卷 / 11期

关键词：

D O I：

10.1016/j.amjcard.2003.08.031

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The prevalence and clinical profile of cardiac troponin T gene mutations were evaluated in 150 consecutive patients with hypertrophic cardiomyopathy from the well-defined geographic region of Tuscany. Troponin T mutations had a low prevalence (3.3%; including a newly described Phe110Leu mutation) and were associated with heterogeneous clinical expression and outcome. (C) 2003 by Excerpta Medica, Inc.

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页码：1358 / 1362

页数：5

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