Casein-based hydrogels: A mini-review

被引:69
作者
Lima Nascimento, Luis Gustavo [1 ]
Casanova, Federico [2 ]
Nogueira Silva, Naaman Francisco [3 ]
de Carvalho Teixeira, Alvaro Vianna Novaes [4 ]
de Carvalho, Antonio Fernandes [1 ]
机构
[1] Univ Fed Vicosa, Dept Tecnol Alimentos, BR-36570900 Vicosa, MG, Brazil
[2] Tech Univ Denmark, Natl Food Inst, Res Grp Food Prod Engn, DK-2800 Lyngby, Denmark
[3] Univ Fed Sao Carlos UFSCar, Ctr Ciencias Nat, BR-18245000 Buri, SP, Brazil
[4] Univ Fed Vicosa, Dept Fis, BR-36570900 Vicosa, MG, Brazil
关键词
Casein; Hydrogel; Drug delivery; Encapsulation; Biomaterial; CROSS-LINKING; CONTROLLED-RELEASE; MICROBIAL TRANSGLUTAMINASE; HYALURONIC-ACID; MICELLES; DELIVERY; ENCAPSULATION; STABILITY; FOOD; GLUTARALDEHYDE;
D O I
10.1016/j.foodchem.2019.126063
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Casein-based hydrogels are biocompatible, biodegradable, renewable, easy to obtain, inexpensive, and nontoxic. They exist in different physicochemical states, e.g. particle hydrogels, which can be dived in suspensions or emulsions and macro hydrogels that are gel colloid type. These biomaterials have drawn increasing attention in recent years due to their abilities to form networks of different tensile strengths and to encapsulate, protect and release biomolecules. This mini-review outlines the recent advances in casein-based hydrogel research and the uses of casein-based hydrogels as drug delivery system for both hydrophobic and hydrophilic molecules. The food and biomedical potential along with possible future uses of the casein-based hydrogels are discussed throughout the document.
引用
收藏
页数:6
相关论文
共 60 条
[11]   Stability of casein micelles cross-linked with genipin: A physicochemical study as a function of pH [J].
Casanova, Federico ;
Nogueira Silva, Naaman F. ;
Gaucheron, Frederic ;
Nogueira, Marcio H. ;
Teixeira, Alvaro V. N. C. ;
Tuler Perrone, Italo ;
Pinhero Alves, Maura ;
Cardoso Fidelis, Priscila ;
de Carvalho, AntOnio F. .
INTERNATIONAL DAIRY JOURNAL, 2017, 68 :70-74
[12]  
Cohen Y, 2017, FOOD FUNCT, V8, P2133, DOI [10.1039/c7fo00323d, 10.1039/C7FO00323D]
[13]   On the structural models of bovine casein micelles-review and possible improvements [J].
Dalgleish, Douglas G. .
SOFT MATTER, 2011, 7 (06) :2265-2272
[14]   The structure of casein micelles: a review of small-angle scattering data [J].
De Kruif, C. G. .
JOURNAL OF APPLIED CRYSTALLOGRAPHY, 2014, 47 :1479-1489
[15]   Water holding capacity and swelling of casein hydrogels [J].
de Kruif, C. G. ;
Anema, Skelte G. ;
Zhu, Changjun ;
Havea, Palatasa ;
Coker, Christina .
FOOD HYDROCOLLOIDS, 2015, 44 :372-379
[16]   Casein micelles and their internal structure [J].
de Kruif, Cornelis G. ;
Huppertz, Thom ;
Urban, Volker S. ;
Petukhov, Andrei V. .
ADVANCES IN COLLOID AND INTERFACE SCIENCE, 2012, 171 :36-52
[17]   Porous Microspheres of Casein/Amorphous Calcium Phosphate Nanocomposite: Room Temperature Synthesis and Application in Drug Delivery [J].
Ding, Guan-Jun ;
Zhu, Ying-Jie ;
Cheng, Guo-Feng ;
Ruan, Yin-Jie ;
Qi, Chao ;
Lu, Bing-Qiang ;
Chen, Feng ;
Wu, Jin .
CURRENT NANOSCIENCE, 2016, 12 (01) :70-78
[18]   Spray-dried casein-based micelles as a vehicle for solubilization and controlled delivery of flutamide: Formulation, characterization, and in vivo pharmacokinetics [J].
Elzoghby, Ahmed O. ;
Helmy, Maged W. ;
Samy, Wael M. ;
Elgindy, Nazik A. .
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2013, 84 (03) :487-496
[19]   Novel Spray-Dried Genipin-Crosslinked Casein Nanoparticles for Prolonged Release of Alfuzosin Hydrochloride [J].
Elzoghby, Ahmed O. ;
Samy, Wael M. ;
Elgindy, Nazik A. .
PHARMACEUTICAL RESEARCH, 2013, 30 (02) :512-522
[20]   Structural mechanisms leading to improved water retention in acid milk gels by use of transglutaminase [J].
Ercili-Cura, Dilek ;
Lille, Martina ;
Legland, David ;
Gaucel, Sebastien ;
Poutanen, Kaisa ;
Partanen, Riitta ;
Lantto, Raija .
FOOD HYDROCOLLOIDS, 2013, 30 (01) :419-427