Preparation of chitin butyrate by using phosphoryl mixed anhydride system

被引：20

作者：

Bhatt, Lok Ranjan ^{[1
]}

Kim, Bo Mi ^{[1
]}

Hyun, Kim ^{[1
]}

Kang, Kyung Hee ^{[1
]}

Lu, Chichong ^{[1
]}

Chai, Kyu Yun ^{[1
]}

机构：

[1] Wonkwang Univ, Sch Nat Sci, Dept Bionanochem, Iksan 570749, Chonbuk, South Korea

来源：

CARBOHYDRATE RESEARCH | 2011年 / 346卷 / 05期

关键词：

Acylation; Chitin butyrate; Butyric acid; Trifluoroacetic anhydride; Phosphoric acid; CHITOSAN; ESTERS;

D O I：

10.1016/j.carres.2011.01.033

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Acylation of chitin with butyric acid was performed in the presence of trifluoroacetic anhydride/phosphoric acid mediated system. The products were characterized by H-1 NMR and FT-IR spectroscopy and their solubility was tested in different organic solvents. Inclusion of butyric acid, moieties into the parent molecule was confirmed from the 1H NMR and FT-IR spectra. FT-IR analysis revealed that the degree of acid substitution (DS) of the products was in a range of 1.9-2.38, which increased with increasing the amounts of butyric acid added to the reaction system. Degree of N-deacetylation (DD) of the products, as determined by 1H NMR was between 54.2% and 65.6%. The products with DS > 2.0 were soluble in dimethyl sulfoxide. N,N-dimethylformamide, tetrahydrofuran, methanol, acetone, chloroform, and acetic acid. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：691 / 694

页数：4

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