Scleroderma "en coup de sabre": pathological evidence of intracerebral inflammation

被引：94

作者：

Stone, J

Franks, AJ

Guthrie, JA

Johnson, MH

机构：

[1] Western Gen Hosp, Dept Clin Neurosci, Edinburgh EH4 2XU, Midlothian, Scotland

[2] Leeds Gen Infirm, Dept Publ Hlth, Div Lab, Serv Radiol, Leeds LS1 3EX, W Yorkshire, England

[3] Leeds Gen Infirm, Dept Publ Hlth, Div Lab, Serv Pharm, Leeds LS1 3EX, W Yorkshire, England

[4] St James Univ Hosp, Dept Radiol, Leeds LS9 7TF, W Yorkshire, England

[5] St James Univ Hosp, Dept Neurol, Leeds LS9 7TF, W Yorkshire, England

来源：

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY | 2001年 / 70卷 / 03期

关键词：

scleroderma "en coup de sabre; central nervous system inflammation; progressive facial hemiatrophy;

D O I：

10.1136/jnnp.70.3.382

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Linear scleroderma "en coup de sabre" (LScs) is associated with neurological complications, the pathogenesis of which is uncertain. A 27 year old woman is reported on who developed epilepsy and focal neurological signs in association with LScs. Brain MRI demonstrated predominantly ipsilateral relapsing and remitting grey and white matter lesions. Analysis of CSF and pathology obtained at brain biopsy provides evidence of an inflammatory process which may be amenable to immunosuppressive treatment.

引用

页码：382 / 385

页数：4

共 22 条

[1] INTRACEREBRAL INVOLVEMENT IN SCLERODERMA EN COUP DE SABRE - REPORT OF A CASE WITH NEUROPATHOLOGIC FINDINGS [J].