Y-chromosome short tandem repeat (STR) haplotypes in a Campania population sample

被引：0
|
作者：
Calcagno, G
Labruna, G
Sacchetti, L
机构：
[1] Univ Naples Federico II, Dipartimento Biochim & Biotecnol Med, Naples, Italy
[2] CEINGE Biotecnol Avanzate, Naples, Italy
来源：
CLINICAL CHEMISTRY AND LABORATORY MEDICINE | 2005年 / 43卷 / 02期
关键词：
capillary electrophoresis; haplotype; short tandem repeats; Y chromosome;
D O I：
10.1515/CCLM.2005.027
中图分类号：
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
Given the lack of information about Y haplotypes for Campania (southern Italy), we analyzed eight Y short tandem repeats in a sample of males from this region with the aim of establishing a Y-haplotype database that can be used for forensic purposes. The eight Y short tandem repeats were amplified by two PCR multiplex reactions: multiplex A for loci DYS19, DYS385, DYS392 and DYS393, and multiplex B for DYS389 I and II, DYS390, DYS391 and DYS385. The proportion of unique haplotypes was 100% (108 Y-chromosome haplotypes in 108 unrelated males) and the haplotype diversity discrimination index was 0.99. These data reflect the high heterogeneity of male lineage in our population and are similar to those obtained in other regions of southern Italy.
引用
收藏
页码：163 / 166
页数：4
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