Trend of blood lactate level in acute aluminum phosphide poisoning

被引：17

作者：

Erfantalab, Peyman ^{[1
]}

Soltaninejad, Kambiz ^{[2
]}

Shadnia, Shahin ^{[1
]}

Zamani, Nasim ^{[1
]}

Hassanian-Moghaddam, Hossein ^{[1
]}

Mandayinejad, Arezou ^{[1
]}

Damaneh, Behrooz Hashemi ^{[1
]}

机构：

[1] Shahid Beheshti Univ Med Sci, Toxicol Res Ctr, Excellent Ctr Clin Toxicol, Dept Clin Toxicol,Loghman Hakim Hosp,Sch Med, Tehran, Iran

[2] Legal Med Org, Dept Forens Toxicol, Legal Med Res Ctr, Tehran, Iran

来源：

WORLD JOURNAL OF EMERGENCY MEDICINE | 2017年 / 8卷 / 02期

关键词：

Aluminum phosphide; Poisoning; Blood lactate; Prognostic factor; EMERGENCY-DEPARTMENT PATIENTS; CRITICALLY-ILL PATIENTS; LACTIC-ACIDOSIS; SERUM LACTATE; MORTALITY; PREDICTOR; HYPERLACTATEMIA; OVERDOSE;

D O I：

10.5847/wjem.j.1920-8642.2017.02.006

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

BACKGROUND: Aluminum phosphide (AlP) poisoning is common in the developing countries. There is no specific antidote for the treatment of acute AlP poisoning. Early diagnosis of poisoning and outcome predictors may facilitate treatment decisions. The objective of this study was to determine the trend of blood lactate level in acute AlP poisoning to evaluate its role as a prognostic factor. METHODS: This was a prospective study on acute AlP intoxicated patients during one year. Demographic data, clinical and laboratory data on admission, and outcome were recorded in a selfmade questionnaire. Blood lactate levels were analyzed every two hours for 24 hours. RESULTS: Thirty-nine (27 male, 12 female) patients were included in the study. The mortality rate was 38.5%. The mean blood pressure, pulse rate, blood pH and serum bicarbonate level were significantly different between the survivors and non-survivors groups. Blood lactate level was significantly higher in the non-survivors group during 8 to 16 hours post ingestion. CONCLUSION: Blood lactate level could be used as an index of severity of acute AlP poisoning.

引用

页码：116 / 120

页数：5

共 27 条

[1] Mitochondrial electron transport chain complexes, catalase and markers of oxidative stress in platelets of patients with severe aluminum phosphide poisoning [J].