Sulfur-containing compounds from Scorodocarpus borneensis and their antimicrobial activity

被引：14
|
作者：
Lim, H [1 ]
Kubota, K
Kobayashi, A
Sugawara, F
机构：
[1] Ochanomizu Univ, Dept Nutr & Food Sci, Bunkyo Ku, Tokyo 112, Japan
[2] Sci Univ Tokyo, Dept Appl Biol Sci, Noda, Chiba 278, Japan
来源：
PHYTOCHEMISTRY | 1998年 / 48卷 / 05期
关键词：
Scorodocarpus borneensis; Olaceae; wood garlic; polysulfides; 2,4,5,7-tetrathiaoctane 4,4-dioxide; 5-thioxo-2,4,6-trithiaheptane 2,2-dioxide; antimicrobial activity;
D O I：
10.1016/S0031-9422(97)00961-8
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Three novel sulfur-containing compounds were isolated from Scorodocarpus borneensis. Their chemical structures were determined to be 2,4,5,7-tetrathiaoctane 4,4-dioxide (CH3SCH2SO2SCH2SCH3, 1) and 5-thioxo-2,4,6-trithiaheptane 2,2-dioxide (CH3SO2CH2SCSSCH3, 2), while the other compound was assumed to be O-ethyl S-methylthiomethyl thiosulfite (CH3SCH2SS(O)OCH2CH3, 3) on the basis of spectroscopic data. This first isolation of compound 1 strongly suggests that S. borneensis possesses a polysulfide formation pathway similar to that of other Allium species. Compounds 1 and 2 exhibited antimicrobial activity against some bacteria and fungi. (C) 1998 Published by Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：787 / 790
页数：4
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