Gut microbiota in obesity

被引:354
作者
Liu, Bing-Nan [1 ]
Liu, Xiao-Tong [1 ]
Liang, Zi-Han [1 ]
Wang, Ji-Hui [1 ,2 ]
机构
[1] Dalian Polytech Univ, Sch Bioengn, 1 Qinggongyuan, Dalian 116034, Liaoning, Peoples R China
[2] Dongguan Univ Technol, Engn Res Ctr Hlth Food Design & Nutr Regulat, Dongguan 523808, Guangdong, Peoples R China
关键词
Gut microbiota; Obesity; Dysbiosis; Genetics; Ecology; DIET-INDUCED OBESITY; INTESTINAL MICROBIOTA; FAT; METABOLISM; OVERWEIGHT; LACTOBACILLUS; TRANSMISSION; ACTIVATION; CAPACITY; WEIGHT;
D O I
10.3748/wjg.v27.i25.3837
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Obesity is a major global health problem determined by heredity and environment, and its incidence is increasing yearly. In recent years, increasing evidence linking obesity to the gut microbiota has been reported. Gut microbiota management has become a new method of obesity treatment. However, the complex interactions among genetics, environment, the gut microbiota, and obesity remain poorly understood. In this review, we summarize the characteristics of the gut microbiota in obesity, the mechanism of obesity induced by the gut microbiota, and the influence of genetic and environmental factors on the gut microbiota and obesity to provide support for understanding the complex relationship between obesity and microbiota. At the same time, the prospect of obesity research related to the gut microbiota is proposed.
引用
收藏
页码:3837 / 3850
页数:14
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