Recent trends in glycopeptide synthesis

被引:15
|
作者
Mizuno, M [1 ]
机构
[1] Noguchi Inst, Itabashi Ku, Tokyo 1730003, Japan
关键词
chemo-enzymatic synthesis; glycoprotein; glycopeptide; glycosyl amino acid; solid-phase synthesis;
D O I
10.4052/tigg.13.11
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Glycoproteins play an important role in biological processes, such as cell recognition, cell adhesion, immunogenic recognition, and so on. Additionally, the carbohydrate moieties of the glycoprotein contribute to the solubility and thermal stability of proteins and to protection against proteolysis (1). In order to study these mechanisms, preparation of glycoproteins is required. In this review, preparation of glycopeptide using conventional chemical and recent manners (chemo-enzymatic method, using of natural source) is described.
引用
收藏
页码:11 / 30
页数:20
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