A perspective on regulation of cell-cell adhesion and epithelial-mesenchymal transition: Known and novel

被引：16

作者：

Khew-Goodall, Y ^{[1
]}

Wadham, C ^{[1
]}

机构：

[1] Inst Med & Vet Sci, Div Human Immunol, Hanson Inst, Adelaide, SA 5000, Australia

来源：

CELLS TISSUES ORGANS | 2005年 / 179卷 / 1-2期

关键词：

EMT; cell-cell adhesion; protein tyrosine phosphatase;

D O I：

10.1159/000084512

中图分类号：

R602 [外科病理学、解剖学]; R32 [人体形态学];

学科分类号：

100101 ;

摘要：

A number of recent reviews in the field have described many of the known growth factors and signalling pathways that may be involved in regulating epithelial-mesenchymal transitions. This perspective will focus on some aspects of posttranslational regulation of cell-cell adhesion that are less well understood and their potential role in initiating epithelial-mesenchymal transitions. In addition, a potential novel intermediate in the signalling pathway of epithelial-mesenchymal transition will also be described. Copyright (C) 2005 S. Karger AG, Basel.

引用

页码：81 / 86

页数：6

共 31 条

[11] Epithelial mesenchymal transition by c-Fos estrogen receptor activation involves nuclear translocation of β-catenin and upregulation of β-catenin/lymphoid enhancer binding factor-1 transcriptional activity [J].

Eger, A ;

Stockinger, A ;

Schaffhauser, B ;

Beug, H ;

Foisner, R .

JOURNAL OF CELL BIOLOGY, 2000, 148 (01) :173-187

[12] Association of human protein tyrosine phosphatase kappa with members of the armadillo family [J].

Fuchs, M ;

Muller, T ;

Lerch, MM ;

Ullrich, A .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (28) :16712-16719

[13] Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex [J].

Fujita, Y ;

Krause, G ;

Scheffner, M ;

Zechner, D ;

Leddy, HEM ;

Behrens, J ;

Sommer, T ;

Birchmeier, W .

NATURE CELL BIOLOGY, 2002, 4 (03) :222-231

[14] Evidence for a function of CtBP in epithelial gene regulation and anoikis [J].

Grooteclaes, ML ;

Frisch, SM .

ONCOGENE, 2000, 19 (33) :3823-3828

[15] Identification of c-MYC as a target of the APC pathway [J].

He, TC ;

Sparks, AB ;

Rago, C ;

Hermeking, H ;

Zawel, L ;

da Costa, LT ;

Morin, PJ ;

Vogelstein, B ;

Kinzler, KW .

SCIENCE, 1998, 281 (5382) :1509-1512

[16] Ubiquitination of a yeast plasma membrane receptor signals its ligand-stimulated endocytosis [J].

Hicke, L ;

Riezman, H .

CELL, 1996, 84 (02) :277-287

[17] Epithelial-mesenchymal transition and its implications for fibrosis [J].

Kalluri, R ;

Neilson, EG .

JOURNAL OF CLINICAL INVESTIGATION, 2003, 112 (12) :1776-1784

[18] Recycling of E-cadherin: A potential mechanism for regulating cadherin dynamics [J].

Le, TL ;

Yap, AS ;

Stow, JL .

JOURNAL OF CELL BIOLOGY, 1999, 146 (01) :219-232

[19] Altered cell adhesion activity by pervanadate due to the dissociation of α-catenin from the E-cadherin catenin complex [J].

Ozawa, M ;

Kemler, R .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (11) :6166-6170

[20] Transforming growth factor β-1 induces snail transcription factor in epithelial cell lines -: Mechanisms for epithelial mesenchymal transitions [J].

Peinado, H ;

Quintanilla, M ;

Cano, A .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (23) :21113-21123

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