A perspective on regulation of cell-cell adhesion and epithelial-mesenchymal transition: Known and novel

被引:16
作者
Khew-Goodall, Y [1 ]
Wadham, C [1 ]
机构
[1] Inst Med & Vet Sci, Div Human Immunol, Hanson Inst, Adelaide, SA 5000, Australia
关键词
EMT; cell-cell adhesion; protein tyrosine phosphatase;
D O I
10.1159/000084512
中图分类号
R602 [外科病理学、解剖学]; R32 [人体形态学];
学科分类号
100101 ;
摘要
A number of recent reviews in the field have described many of the known growth factors and signalling pathways that may be involved in regulating epithelial-mesenchymal transitions. This perspective will focus on some aspects of posttranslational regulation of cell-cell adhesion that are less well understood and their potential role in initiating epithelial-mesenchymal transitions. In addition, a potential novel intermediate in the signalling pathway of epithelial-mesenchymal transition will also be described. Copyright (C) 2005 S. Karger AG, Basel.
引用
收藏
页码:81 / 86
页数:6
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