Childhood B-Cell Acute Lymphoblastic Leukemia Following SARS CoV-2 Infection: A Potential Second "Hit" in Leukemogenesis

被引：0

作者：

Persaud, Yogindra ^{[1
]}

Shamoun, Mark ^{[1
,3
]}

Chitlur, Meera ^{[1
,3
]}

Des Rosier, Kyle J. ^{[1
]}

Taub, Jeffrey W. ^{[1
,2
,3
]}

机构：

[1] Childrens Hosp Michigan, Div Hematol Oncol, Detroit, MI 48201 USA

[2] Wayne State Univ, Sch Med, Dept Pediat, Detroit, MI 48201 USA

[3] Cent Michigan Univ, Dept Pediat, Mount Pleasant, MI USA

来源：

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY | 2021年 / 43卷 / 08期

关键词：

ALL; B-ALL; childhood leukemia; B-cell lymphoblastic leukemia; delayed infectious theory; COVID-19; SARS CoV-2; LACTATE-DEHYDROGENASE; CHILDREN; CANCER; VIRUS;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The Coronavirus Disease 2019 (COVID-19) pandemic has become the worst pandemic in modern history. The lack of prior immunity to the virus has resulted in a high mortality rate, though children have fared better than adults, overall. We present a case of a child who developed B-cell acute lymphoblastic leukemia 1 week following a symptomatic COVID-19 infection. It is possible that this viral infection provided the "second hit" posited to occur in pediatric leukemogenesis as proposed by Dr Greaves, with his initial viral exposure occurring several weeks earlier.

引用

页码：E1241 / E1243

页数：3

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