The effect of normobaric hyperoxia on cardiac index in healthy awake volunteers

被引:49
作者
Harten, JM
Anderson, KJ
Angerson, WJ
Booth, MG
Kinsella, J
机构
[1] Univ Glasgow, Dept Anaesthesia, Glasgow G31 2ER, Lanark, Scotland
[2] Univ Glasgow, Dept Surg, Glasgow Royal Infirm, Glasgow G31 2ER, Lanark, Scotland
关键词
Cardiac output; hyperoxia;
D O I
10.1046/j.1365-2044.2003.03333.x
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Fifteen healthy volunteers were exposed to a stepwise increase in FIO2 between 0.21 and 1.0, and their haemodynamic responses were measured with a non-invasive transthoracic bio-impedance monitor. There was mean reduction in cardiac index from 3.44 to 3.08 l.min(-1).m(-2) (10.7%, p<0.001). The mean reduction in heart rate was from 77.3 to 69.1 beats.min(-1) (10.5%, p<0.001) and the mean systemic vascular index increased from 2062 to 2221 dyne.s(-1).cm(-5).m(-2) (7.7%, p<0.025). There were no significant changes in stroke index or mean arterial pressure. These changes are similar quantitatively and qualitatively to those previously reported by dye dilution techniques.
引用
收藏
页码:885 / 888
页数:4
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