Design and evaluation of a novel breast cancer detection system combining both thermoacoustic, (TA) and photoacoustic, (PA) tomography

被引:167
作者
Pramanik, Manojit [1 ]
Ku, Geng [1 ]
Li, Changhui [1 ]
Wang, Lihong V. [1 ]
机构
[1] Washington Univ, Dept Biomed Engn, Opt Imaging Lab, St Louis, MO 63130 USA
基金
美国国家卫生研究院;
关键词
40;
D O I
10.1118/1.2911157
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
We have developed a novel scanner for breast cancer detection, integrating both thermoacoustic and photoacoustic techniques to achieve dual contrast (microwave and light absorption) imaging. This scanner is nonionizing, low cost, and can potentially provide high-resolution, dual modality threedimensional images of the breast. The scanner uses front instead of side breast compression and dry instead of gel ultrasonic coupling. Here we present the design of the breast scanner along with initial tissue phantom study results as a precursor to an actual patient study. (C) 2008 American Association of Physicists in Medicine.
引用
收藏
页码:2218 / 2223
页数:6
相关论文
共 41 条
[1]   Novel receptor-targeted fluorescent contrast agents for in vivo tumor imaging [J].
Achilefu, S ;
Dorshow, RB ;
Bugaj, JE ;
Rajagopalan, R .
INVESTIGATIVE RADIOLOGY, 2000, 35 (08) :479-485
[2]  
[Anonymous], 1986, Medical Applications of Microwave Imaging
[3]  
[Anonymous], 1999, C951 IEEE
[4]  
CHAUDHARY SS, 1984, INDIAN J BIOCHEM BIO, V21, P76
[5]   Microwave system for breast tumor detection [J].
Fear, EC ;
Stuchly, MA .
IEEE MICROWAVE AND GUIDED WAVE LETTERS, 1999, 9 (11) :470-472
[6]   MEDICAL PROGRESS .2. BREAST-CANCER [J].
HARRIS, JR ;
LIPPMAN, ME ;
VERONESI, U ;
WILLETT, W .
NEW ENGLAND JOURNAL OF MEDICINE, 1992, 327 (06) :390-398
[7]  
HOMBURGER F, 1959, PHYSIOPATHOLOGY CANC
[8]   MICROWAVE TIME-DELAY SPECTROSCOPIC IMAGERY OF ISOLATED CANINE KIDNEY [J].
JACOBI, JH ;
LARSEN, LE .
MEDICAL PHYSICS, 1980, 7 (01) :1-7
[9]  
KREMKAU FW, 1993, DIAGNOSTIC ULTRASOUN
[10]   Thermoacoustic CT with radio waves: A medical imaging paradigm [J].
Kruger, RA ;
Kopecky, KK ;
Aisen, AM ;
Reinecke, DR ;
Kruger, GA ;
Kiser, WL .
RADIOLOGY, 1999, 211 (01) :275-278