Maturation of prepulse inhibition (PPI) in childhood

被引：23
|
作者：
Gebhardt, J. [1 ]
Schulz-Juergensen, S. [2 ]
Eggert, P. [2 ]
机构：
[1] Univ Leipzig, Hosp Children & Adolescents, Dept Pediat, D-04103 Leipzig, Germany
[2] Univ Clin Schleswig Holstein, Dept Pediat, Kiel, Germany
来源：
PSYCHOPHYSIOLOGY | 2012年 / 49卷 / 04期
关键词：
Children; Infants; EMG; Startle blink; Normal volunteers; INDUCED STARTLE MODULATION; NOCTURNAL ENURESIS; REFLEX; NEUROBIOLOGY; INFANT;
D O I：
10.1111/j.1469-8986.2011.01323.x
中图分类号：
B84 [心理学];
学科分类号：
04 ; 0402 ;
摘要：
It is known that sensorimotor gating measured by the prepulse inhibition of the startle reflex (PPI) matures during childhood. Since certain disorders in children, for example, enuresis, show a significant loss in PPI, the PPI as a tool for investigating brainstem reflex control mechanism gains in importance. Therefore, it is crucial to know the natural course of PPI maturation in childhood. A total of 122 healthy children aged from 310 years and 10 healthy adults were examined. PPI was initiated by a 120?ms and a 60?ms prepulse and was measured by the EMG of M. orbicularis oculi. For the respective prepulse intervals, the PPI level in each age group increased from 3 to 9 or 10 years and showed a similar course. The findings confirm and extend knowledge about the maturation of PPI during childhood and emphasize the importance of age-dependent standard values when investigating PPI in children.
引用
收藏
页码：484 / 488
页数：5
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