Infection by Toxoplasma gondii represents a risk to fetal development during pregnancy. In this study, the serological profile of pregnant women from different regions of Bahia. Brazil, was determined. Tests were conducted at LACEN-BA (Salvador, Brazil). The mean age of the women was 24.5 years (+/- 7.41 years) and 56.4% were positive for IgG and negative for IgM specific for T. gondii. Seronegative women represented 35.9% of the total (IgG- and IgM-negative) and inconclusive results comprised 4%. Differences were observed in distinct regions. Therefore, a preventive action must be reinforced in specific regions aimed at early diagnosis to minimise the risk of congenital toxoplasmosis development. (C) 2011 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.