Structure and absolute configuration of a secolignan from Peperomia blanda

被引：17

作者：

Felippe, Lidiane G. ^{[1
]}

Batista, Joao M., Jr. ^{[1
]}

Baldoqui, Debora C. ^{[2
]}

Nascimento, Isabele R. ^{[1
]}

Kato, Massuo J. ^{[3
]}

Bolzani, Vanderlan S. ^{[1
]}

Furlan, Maysa ^{[1
]}

机构：

[1] Univ Estadual Paulista UNESP, Inst Quim, BR-14800900 Araraquara, SP, Brazil

[2] Univ Estadual Maringa, Dept Quim, BR-87020900 Maringa, PR, Brazil

[3] Univ Sao Paulo, Inst Quim, BR-05599970 Sao Paulo, Brazil

来源：

PHYTOCHEMISTRY LETTERS | 2011年 / 4卷 / 03期

基金：

巴西圣保罗研究基金会;

关键词：

Peperomia blanda; Piperaceae; Secolignan; Absolute configuration; Electronic circular dichroism; Density functional theory; LIGNANS; ANALOGS;

D O I：

10.1016/j.phytol.2011.04.007

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

A secolignan, (-)-2-methyl-3-[bis(3 ',4 '-methylenedioxy-5 '-methoxyphenyl) methyl] butyrolactone (1), with a rare cis configuration was isolated from the aerial parts of Peperomia blanda (Piperaceae). The structure of this compound was elucidated by a combination of spectroscopic methods, including ultraviolet, infrared, 1D- and 2D- nuclear magnetic resonance as well as high resolution mass spectrometry data. The absolute configuration of (-)-1 was determined as (2R,3S) by the comparison of experimental electronic circular dichroism (ECD) spectroscopy and time-dependent density functional theory (TDDFT) calculations. (C) 2011 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.

引用

页码：245 / 249

页数：5

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