A national survey of polybrominated diphenyl ethers (PBDEs) and indicator polychlorinated biphenyls (PCBs) in Chinese mothers' milk

被引：67

作者：

Zhang, Lei ^{[1
,2
]}

Li, Jingguang ^{[1
]}

Zhao, Yunfeng ^{[1
]}

Li, Xiaowei ^{[1
]}

Yang, Xin ^{[1
]}

Wen, Sheng ^{[1
,3
]}

Cai, Zongwei ^{[2
]}

Wu, Yongning ^{[1
]}

机构：

[1] Chinese Ctr Dis Control & Prevent, Key Lab Chem Safety & Hlth, Natl Inst Nutr & Food Safety, Beijing 100050, Peoples R China

[2] Hong Kong Baptist Univ, Dept Chem, Kowloon Tong, Hong Kong, Peoples R China

[3] Hubei Prov Ctr Dis Control & Prevent, Wuhan 430079, Peoples R China

来源：

CHEMOSPHERE | 2011年 / 84卷 / 05期

关键词：

Polybrominated diphenyl ethers; Indicator polychlorinated biphenyls; Human milk; Body burden; Risk assessment; HUMAN BREAST-MILK; BROMINATED FLAME RETARDANTS; CONGENER-SPECIFIC PROFILES; CORD SERUM; ORGANOCHLORINE PESTICIDES; JAPANESE MOTHERS; MATERNAL SERUM; ADIPOSE-TISSUE; EXPOSURE; WOMEN;

D O I：

10.1016/j.chemosphere.2011.03.041

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Seven polybrominated diphenyl ethers (PBDEs) congeners (BDE-28, BDE-47, BDE-99, BDE-100, BDE-153, BDE-154 and BDE-183) and six indicator polychlorinated biphenyls (PCBs) congeners (CB-28, CB-52, CB-101, CB-138, CB-153 and CB-180) were measured in 24 pooled human milk samples comprised of 1237 individual samples from 12 provinces in China. The samples were taken to estimate the background body burden of general population and assess nursing infant exposure via human milk in China. The median concentrations of Sigma(7)PBDEs and Sigma(6)PCBs were 1.49 and 10.50 ng g(-1) lipid weight (lw), respectively. BDE-28. BDE-47 and BDE-153 were predominant PBDE congeners accounting for nearly 70% of Sigma(7)PBDEs. As for indicator PCBs, CB-153 was the most abundant congener, followed by CB-138. In our study, there was no significantly statistical relationship between concentrations of PBDEs in milk samples and maternal age as well as dietary habits. Sigma(7)PBDEs did not correlate to Sigma(6)PCBs in Chinese mothers' milk. The human exposure to indicator PCBs in China was found to be significantly determined by maternal age, dietary habits and geographical factors. It is suggested that Chinese general population is probably exposed to PBDEs with multiple sources and pathways. The estimated daily intakes (EDI) of BDE-47, BDE-99 and BDE-153 for the Chinese nursing infant were much lower than corresponding threshold reference values suggested by USEPA. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：625 / 633

页数：9

共 65 条

[1] Time-trend (1973-2000) of polybrominated diphenyl ethers in Japanese mother's milk [J].

Akutsu, K ;

Kitagawa, M ;

Nakazawa, H ;

Makino, T ;

Iwazaki, K ;

Oda, H ;

Hori, S .

CHEMOSPHERE, 2003, 53 (06) :645-654

[2] Personal exposure to Polybrominated Diphenyl Ethers (PBDEs) in residential indoor air [J].

Allen, Joseph G. ;

McClean, Michael D. ;

Stapleton, Heather M. ;

Nelson, Jessica W. ;

Webster, Thomas F. .

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2007, 41 (13) :4574-4579

[3]

[Anonymous], 2026121803 UFOPLAN

[4]

[Anonymous], 2007, Fourth WHO-coordinated survey of human milk for persistent organic pollutants in cooperation with UNEP guidelines for developing a national protocol

[5] Exposure assessment of French women and their newborn to brominated flame retardants: Determination of tri- to deca- polybromodiphenylethers (PBDE) in maternal adipose tissue, serum, breast milk and cord serum [J].