Synthesis, Characterization, and Biological Activities of Lanthanide(III) Complexes of β-Diketone Hydrazone Derivatives

A series of beta-diketone hydrazone derivatives has been synthesized through condensation of beta-diketone with aromatic aldehydes followed by reaction with phenylhydrazine. The structures of the ligands and intermediates are well defined through elemental and spectroscopic analyses. These hydrazones are potential ligands toward lanthanide metal ions. New complexes of trivalent scandium, yttrium, lanthanum, and cerium have been synthesized. The composition of these complexes is discussed on the basis of elemental analyses, infrared (IR) spectroscopy, magnetic moments and thermal analyses. The ligands are supposed to be bidentate with the two-sp2 nitrogen atoms. The prepared (1:1) metal: ligand complexes were screened for antibacterial and antifungal properties and have exhibited potential activity. Scandium(III) complexes are more active toward bacterium, yeast, and fungi.