New technology for improved vaccine safety and efficacy

被引：14

作者：

Roth, JA ^{[1
]}

Henderson, LM

机构：

[1] Iowa State Univ, Coll Vet Med, Dept Vet Microbiol & Prevent Med, Ames, IA 50011 USA

[2] USDA, Vet Serv, Anim & Plant Hlth Inspect Serv, Ctr Vet Biol Licensing & Policy Dev, Ames, IA 50010 USA

来源：

VETERINARY CLINICS OF NORTH AMERICA-FOOD ANIMAL PRACTICE | 2001年 / 17卷 / 03期

关键词：

D O I：

10.1016/S0749-0720(15)30008-6

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

Nearly all of the 2000 vaccines presently licensed by the US Department of Agriculture for veterinary use in the United States are conventional vaccines containing either killed or modified live whole bacteria or viruses. Recent advances in molecular biology, immunology, microbiology, and genetics and in understanding microbial pathogenesis have led to the development of a wide variety of new approaches for developing safer and more effective vaccines. This article briefly describes these new technologies and their potential advantages and disadvantages as compared with conventional killed and modified live vaccines.

引用

页码：585 / +

页数：14

共 40 条

[1] Biased immunoglobulin G1 isotype responses induced in cattle with DNA expressing msp1a of Anaplasma marginale [J].

Arulkanthan, A ;

Brown, WC ;

McGuire, TC ;

Knowles, DP .

INFECTION AND IMMUNITY, 1999, 67 (07) :3481-3487

[2] Field use of a vaccinia-rabies recombinant vaccine for the control of sylvatic rabies in Europe and North America [J].

Brochier, B ;

Aubert, MFA ;

Pastoret, PP ;

Masson, E ;

Schon, J ;

Lombard, M ;

Chappuis, G ;

Languet, B ;

Desmettre, P .

REVUE SCIENTIFIQUE ET TECHNIQUE-OFFICE INTERNATIONAL DES EPIZOOTIES, 1996, 15 (03) :947-970

[3]

Castañón S, 1999, J VIROL, V73, P4452

[4] BOVINE HERPESVIRUS-1 - IMMUNE-RESPONSES IN MICE AND CATTLE INJECTED WITH PLASMID DNA [J].

COX, GJM ;

ZAMB, TJ ;

BABIUK, LA .

JOURNAL OF VIROLOGY, 1993, 67 (09) :5664-5667

[5] Adjuvants - A classification and review of their modes of action [J].

Cox, JC ;

Coulter, AR .

VACCINE, 1997, 15 (03) :248-256

[6]

DANGLER CA, 1993, AM J VET RES, V54, P540

[7] BIOCHEMICAL AND IMMUNOLOGICAL CHARACTERIZATION OF A NOVEL PEPTIDE CARRIER SYSTEM USING ROTAVIRUS VP6 PARTICLES [J].

FRENCHICK, PJ ;

SABARA, MIJ ;

READY, KFM ;

BABIUK, LA .

VACCINE, 1992, 10 (11) :783-791

[8] USE OF DNA ENCODING INFLUENZA HEMAGGLUTININ AS AN AVIAN INFLUENZA VACCINE [J].

FYNAN, EF ;

ROBINSON, HL ;

WEBSTER, RG .

DNA AND CELL BIOLOGY, 1993, 12 (09) :785-789

[9] Fetal immunization by a DNA vaccine delivered into the oral cavity [J].

Gerdts, V ;

Babiuk, LA ;

Littel-van den Hurk, SV ;

Griebel, PJ .

NATURE MEDICINE, 2000, 6 (08) :929-932

[10]

Harpin S, 1997, FEMS MICROBIOL LETT, V146, P229, DOI 10.1111/j.1574-6968.1997.tb10198.x

← 1 2 3 4 →