Initial experience of videocapsule endoscopy for diagnosing small-bowel, tumors in patients with GI polyposis syndromes

被引：32

作者：

Barkay, O ^{[1
]}

Moshkowitz, M ^{[1
]}

Fireman, Z ^{[1
]}

Shemesh, E ^{[1
]}

Goldray, O ^{[1
]}

Revivo, M ^{[1
]}

Kessler, A ^{[1
]}

Halpern, Z ^{[1
]}

Orr-Urtreger, A ^{[1
]}

Arber, N ^{[1
]}

机构：

[1] Tel Aviv Univ, Dept Canc Prevent, Tel Aviv Sourasky Med Ctr, Sackler Fac Med, IL-64239 Tel Aviv, Israel

来源：

GASTROINTESTINAL ENDOSCOPY | 2005年 / 62卷 / 03期

关键词：

D O I：

10.1016/S0016-5107(05)01582-8

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Background: Small-bowel tumors frequently occur in familial adenomatous polyposis and other GI poly syndromes. These tumors are difficult to detect with conventional techniques. Our aim was to assess the utility of videocapsule endoscopy in the detection of small-bowel tumors in this setting. Methods: We examined 19 familial adenomatous polyposis patients and 3 patients with either Peutz-Jeghers syndrome, hyperplastic polyposis, or Cowden disease. Observations: Prevalence of small-bowel polyps on videocapsule endoscopy was 59% in all patients, 52'6% in familial adenomatous polyposis patients, and 75% in a subgroup of familial adenomatous polyposis patients with exon 15 mutations. Videocapsule endoscopy was safe and well tolerated in all patients. Conclusions: Videocapsule endoscopy has a high yield in detecting small-bowel tumors in patients with GI polyposis syndromes. It may be especially indicated in familial adenomatous polyposis patients with the aggressive phenotype of the disease, e.g., mutations in exon 15.

引用

页码：448 / 452

页数：5

共 21 条

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