Isolation and structure elucidation of a new amphidinol with a truncated polyhydroxyl chain from Amphidinium klebsii

被引：71

作者：

Morsy, N

Matsuoka, S

Houdai, T

Matsumori, N

Adachi, S

Murata, M ^{[1
]}

Iwashita, T

Fujita, T

机构：

[1] Osaka Univ, Grad Sch Sci, Dept Chem, Toyonaka, Osaka 5600043, Japan

[2] Suntory Inst Bioorgan Res, Shimamoto, Osaka 6188503, Japan

来源：

TETRAHEDRON | 2005年 / 61卷 / 36期

关键词：

amphidinol; amphidinium; AM7; AM3; CID MS/MS;

D O I：

10.1016/j.tet.2005.07.004

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new member of amphidinols (AM7) possessing a polyene-polyhydroxyl structure with the shortest carbon backbone and sulfate ester was isolated from the cultured dinoflagellate, Amphidinium klebsii. AM7 showed hemolytic and antifungal activities. The structure was elucidated on the basis of 2D NMR data in combination with CID MS/MS experiments. (c) 2005 Elsevier Ltd. All rights reserved.

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收藏

页码：8606 / 8610

页数：5

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