Myasthenia gravis: An unrecognized cause of head drop in Parkinson's disease

被引:23
作者
Fasano, A. [1 ]
Evoli, A. [1 ]
Piano, C. [1 ]
Tonali, P. A. [1 ,2 ]
Bentivoglio, A. R. [1 ]
机构
[1] Univ Cattolica Sacro Cuore, Ist Neurol, Rome, Italy
[2] Fdn Don Carlo Gnocchi, Milan, Italy
关键词
Parkinson's disease; myasthenia gravis; head drop; camptocormia;
D O I
10.1016/j.parkreldis.2007.02.009
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Head drop is characterized by marked anterior flexion of the cervical spine, caused by weakness of the neck extensors or by increased tone of the flexor muscles. We report a woman with Parkinson's disease and head drop not due to cervical dystonia (a common cause of antecollis in parkinsonisms). Clinical, radiological, and neurophysiological features together with responsiveness to anticholinesterases and plasma exchanges indicated the possibility of a concomitant myasthenia gravis. (C) 2007 Elsevier Ltd. All rights reserved.
引用
收藏
页码:164 / 165
页数:2
相关论文
共 9 条
[1]   Dropped-head syndrome due to isolated myositis of neck extensor muscles: MRI findings [J].
Gaeta, M ;
Mazziotti, S ;
Toscano, A ;
Rodolico, C ;
Mazzeo, A ;
Blandino, A .
SKELETAL RADIOLOGY, 2006, 35 (02) :110-112
[2]  
KAO KP, 1993, CLIN NEUROL NEUROSUR, V95, P137
[3]   Parkinson's disease associated with myasthenia gravis - A report of 4 cases [J].
Levin, N ;
Karussis, D ;
Abramsky, O .
JOURNAL OF NEUROLOGY, 2003, 250 (06) :766-767
[4]   EDROPHONIUM RESPONSIVENESS NOT NECESSARILY DIAGNOSTIC OF MYASTHENIA-GRAVIS [J].
OH, SJ ;
CHO, HK .
MUSCLE & NERVE, 1990, 13 (03) :187-191
[5]  
Petiot P, 1997, REV NEUROL, V153, P251
[6]   The dropped head sign: an unusual presenting feature of myasthenia gravis [J].
Puruckherr, M ;
Pooyan, P ;
Dube, D ;
Byrd, RP ;
Roy, TM .
NEUROMUSCULAR DISORDERS, 2004, 14 (06) :378-379
[7]  
Tasic Z, 1991, Srp Arh Celok Lek, V119, P103
[8]   PARKINSONS-DISEASE AND MYASTHENIA-GRAVIS - ADVERSE EFFECT OF TRIHEXYPHENIDYL ON NEUROMUSCULAR-TRANSMISSION [J].
UENO, S ;
TAKAHASHI, M ;
KAJIYAMA, K ;
OKAHISA, N ;
HAZAMA, T ;
YORIFUJI, S ;
TARUI, S .
NEUROLOGY, 1987, 37 (05) :832-833
[9]   Head drop and camptocormia [J].
Umapathi, T ;
Chaudhry, V ;
Cornblath, D ;
Drachman, D ;
Griffin, J ;
Kuncl, R .
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 2002, 73 (01) :1-7