It Is Not About the Bike, It Is About the Pedaling: Forced Exercise and Parkinson's Disease

被引：140

作者：

Alberts, Jay L. ^{[1
,3
]}

Linder, Susan M. ^{[1
,3
]}

Penko, Amanda L. ^{[1
,3
]}

Lowe, Mark J. ^{[2
]}

Phillips, Micheal ^{[2
]}

机构：

[1] Cleveland Clin Fdn, Ctr Neurol Restorat, Dept Biomed Engn, Cleveland, OH 44195 USA

[2] Cleveland Clin Fdn, Imaging Inst, Cleveland, OH 44195 USA

[3] L Stokes Cleveland VA Med Ctr, Cleveland FES Ctr, Cleveland, OH USA

来源：

EXERCISE AND SPORT SCIENCES REVIEWS | 2011年 / 39卷 / 04期

关键词：

forced exercise; aerobic exercise; fMRI; motor function; neuroprotection; rehabilitation; BASAL GANGLIA; BEHAVIORAL RECOVERY; NEUROPLASTICITY; RELIABILITY; STIMULATION; VOLUNTARY; THERAPY; MODELS; SRM;

D O I：

10.1097/JES.0b013e31822cc71a

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

ALBERTS, J.L., S.M. LINDER, A.L. PENKO, M.J. LOWE, and M. PHILLIPS. It is not about the bike, it is about the pedaling: forced exercise and parkinson's disease. Exerc. Sport Sci. Rev., Vol. 39, No. 4, pp. 177-186, 2011. Forced exercise has resulted in neuroprotective effects and improved motor function in animal studies. These promising results have not yet been translated fully to humans with Parkinson's disease (PD), as traditional exercise interventions have not yielded global improvements in function. A novel forced exercise intervention is described that has resulted in improved motor function and central nervous system function in PD patients.

引用

页码：177 / 186

页数：10

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