The risk of exposure to diagnostic ultrasound in postnatal subjects - Thermal effects

被引:57
作者
O'Brien, William D. [1 ]
Deng, Cheri X. [3 ]
Harris, Gerald R. [4 ]
Herman, Bruce A. [4 ]
Merritt, Christopher R. [5 ]
Sanghvi, Naren [6 ]
Zachary, James F. [2 ]
机构
[1] Univ Illinois, Dept Elect & Comp Engn, Bioacoust Res Lab, Urbana, IL 61801 USA
[2] Univ Illinois, Dept Pathobiol, Urbana, IL 61801 USA
[3] Case Western Reserve Univ, Dept Biomed Engn, Cleveland, OH 44106 USA
[4] US FDA, Ctr Devices & Radiol Hlth, Rockville, MD 20857 USA
[5] Thomas Jefferson Univ Hosp, Dept Radiol, Philadelphia, PA 19107 USA
[6] Focus Surg Inc, Indianapolis, IN USA
关键词
arrhenius analysis; nonfetal tissue; output display standard; temperature increase threshold; thermal mechanism;
D O I
10.7863/jum.2008.27.4.517
中图分类号
O42 [声学];
学科分类号
070206 ; 082403 ;
摘要
T his review evaluates the thermal mechanism for ultrasound-induced biological effects in postnatal subjects. The focus is the evaluation of damage versus temperature increase. A view of ultrasound-induced temperature increase is presented, based on thermodynamic Arrhenius analyses. The hyperthermia and other literature revealed data that allowed for an estimate of a temperature increase threshold of tissue damage for very short exposure times. This evaluation yielded an exposure time extension of the 1997 American Institute of Ultrasound in Medicine Conclusions Regarding Heat statement (American Institute of Ultrasound in Medicine, Laurel, MD) to 0.1 second for nonfetal tissue, where, at this exposure time, the temperature increase threshold of tissue damage was estimated to be about 18 degrees C. The output display standard was also evaluated for soft tissue and bone cases, and it was concluded that the current thermal indices could be improved to reduce the deviations and scatter of computed maximum temperature rises.
引用
收藏
页码:517 / 535
页数:19
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