Clean and atom-economic synthesis of α-phenylselenoacrylonitriles and α-phenylseleno-α,β-unsaturated esters by Knoevenagel reaction under solvent-free conditions

被引：30

作者：

Perin, G ^{[1
]}

Jacob, RG

Botteselle, GV

Kublik, EL

Lenardao, EJ

Cella, R

dos Santos, PCS

机构：

[1] Univ Fed Pelotas, Dept Quim Organ, BR-96010900 Pelotas, Brazil

[2] Univ Fed Pelotas, Dept Quim Anal & Inorgan, BR-96010900 Pelotas, Brazil

[3] Univ Fed Santa Maria, Dept Quim, Santa Maria, RS, Brazil

来源：

JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY | 2005年 / 16卷 / 04期

关键词：

solvent-free reaction; Knoevenagel condensation; phenylselenoacrylonitriles;

D O I：

10.1590/S0103-50532005000500027

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A simple, clean and efficient method has been developed for the synthesis of alpha-phenylselenoacrylonitriles and alpha-phenylseleno-alpha,beta-unsaturated esters by a one-pot reaction of aldehydes with phenylselenoacetonitrile or ethyl (phenyl seleno) acetate respectively, in the presence of a solid supported catalyst (KF/Al2O3), without any solvent.

引用

页码：857 / 862

页数：6

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