Hypovitaminosis D and Aging: Is There a Role in Muscle and Brain Health?

被引:20
作者
D'Amelio, Patrizia [1 ,2 ]
Quacquarelli, Luca [2 ]
机构
[1] CHU Vaudois, Serv Geriatrie & Readaptat Geriatr, CH-1011 Lausanne, Switzerland
[2] Univ Torino, Geriatr & Bone Dis Unit, Dept Internal Med, I-10126 Turin, Italy
关键词
vitamin D; brain; muscle; aging; VITAMIN-D DEFICIENCY; DWELLING OLDER-ADULTS; D-RECEPTOR GENE; SKELETAL-MUSCLE; D SUPPLEMENTATION; CALCIUM SUPPLEMENTATION; 25-HYDROXYVITAMIN D; SARCOPENIA; STRENGTH; EXPRESSION;
D O I
10.3390/nu12030628
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
The older-adult population is constantly increasing, hence aging and mechanisms leading to aging are a topic raising increasing interest. Hypovitaminosis D is common amongst old patients and has been proposed as causative of several chronic diseases. Here we review the role of hypovitaminosis D and vitamin D supplementation in sarcopenia and dementia, from bench to bedside.
引用
收藏
页数:11
相关论文
共 75 条
[1]   Does vitamin-D intake during resistance training improve the skeletal muscle hypertrophic and strength response in young and elderly men? - a randomized controlled trial [J].
Agergaard, Jakob ;
Trostrup, Jeanette ;
Uth, Jacob ;
Iversen, Jonas Vestergard ;
Boesen, Anders ;
Andersen, Jesper L. ;
Schjerling, Peter ;
Langberg, Henning .
NUTRITION & METABOLISM, 2015, 12
[2]   Developmental vitamin D deficiency alters brain protein expression in the adult rat:: Implications for neuropsychiatric disorders [J].
Almeras, Lionel ;
Eyles, Darryl ;
Benech, Philippe ;
Laffite, Daniel ;
Villard, Claude ;
Patatian, Angela ;
Boucraut, Jose ;
Mackay-Sim, Alan ;
McGrath, John ;
Feron, Francois .
PROTEOMICS, 2007, 7 (05) :769-780
[3]   Evidence for a U-Shaped Relationship Between Prehospital Vitamin D Status and Mortality: A Cohort Study [J].
Amrein, Karin ;
Quraishi, Sadeq A. ;
Litonjua, Augusto A. ;
Gibbons, Fiona K. ;
Pieber, Thomas R. ;
Camargo, Carlos A., Jr. ;
Giovannucci, Edward ;
Christopher, Kenneth B. .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2014, 99 (04) :1461-1469
[4]   Hypovitaminosis D and Executive Dysfunction in Older Adults with Memory Complaint: A Memory Clinic-Based Study [J].
Annweiler, Cedric ;
Maby, Elodie ;
Meyerber, Marine ;
Beauchet, Olivier .
DEMENTIA AND GERIATRIC COGNITIVE DISORDERS, 2014, 37 (5-6) :286-293
[5]  
[Anonymous], WORLD ALZH REP 2018
[6]   Vitamin D Deficiency Is Associated With Impaired Muscle Strength And Physical Performance In Community-Dwelling Older Adults: Findings From The English Longitudinal Study Of Ageing [J].
Aspell, Niamh ;
Laird, Eamon ;
Healy, Martin ;
Lawlor, Brain ;
O'Sullivan, Maria .
CLINICAL INTERVENTIONS IN AGING, 2019, 14 :1751-1760
[7]   Epidemiology of sarcopenia among the elderly in New Mexico [J].
Baumgartner, RN ;
Koehler, KM ;
Gallagher, D ;
Romero, L ;
Heymsfield, SB ;
Ross, RR ;
Garry, PJ ;
Lindeman, RD .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 1998, 147 (08) :755-763
[8]   Effects of Vitamin D and Calcium Fortified Yogurts on Gait, Cognitive Performances, and Serum 25-Hydroxyvitamin D Concentrations in Older Community-Dwelling Females: Results from the GAit, MEmory, Dietary and Vitamin D (GAME-D2) Randomized Controlled Trial [J].
Beauchet, Olivier ;
Launay, Cyrille P. ;
Galery, Kevin ;
Vilcocq, Christine ;
Dontot-Payen, Flore ;
Rousseau, Brigitte ;
Benoit, Valerie ;
Allali, Gilles .
NUTRIENTS, 2019, 11 (12)
[9]   Calcium ion in skeletal muscle:: Its crucial role for muscle function, plasticity, and disease [J].
Berchtold, MW ;
Brinkmeier, H ;
Müntener, M .
PHYSIOLOGICAL REVIEWS, 2000, 80 (03) :1215-1265
[10]   Vitamin D Deficiency-Induced Muscle Wasting Occurs through the Ubiquitin Proteasome Pathway and Is Partially Corrected by Calcium in Male Rats [J].
Bhat, Mehrajuddin ;
Kalam, Ramesh ;
Qadri, Syed S. Y. H. ;
Madabushi, Seshacharyulu ;
Ismail, Ayesha .
ENDOCRINOLOGY, 2013, 154 (11) :4018-4029