Lichen planopilaris and frontal fibrosing alopecia: review and update of diagnostic and therapeutic features

被引:25
|
作者
Costa Fechine, Carolina Oliveira [1 ]
Sakai Valente, Neusa Yuriko [1 ]
Romiti, Ricardo [1 ]
机构
[1] Univ Sao Paulo, Fac Med, Dept Dermatol, Sao Paulo, SP, Brazil
关键词
Alopecia; Diagnosis; Lichen planus; Review; Scalp dermatoses; Therapeutics; RETROSPECTIVE ANALYSIS; HYDROXYCHLOROQUINE; ISOTRETINOIN; EFFICACY; SCALP;
D O I
10.1016/j.abd.2021.08.008
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Lichen planopilaris and frontal fibrosing alopecia are primary scarring alopecias where diagnosis can be suggested by clinical and trichoscopy features, especially in the early stages, but scalp biopsy is the standard exam for definitive diagnosis. Frontal fibrosing alopecia is considered a variant of lichen planopilaris, as the histopathological findings are similar, with a perifollicular lymphohistiocytic infiltrate, sometimes with a lichenoid pattern. A thorough clinical examination, trichoscopy and photographic documentation are essential to assess the evolution and therapeutic response. To date, there are no validated treatments or guidelines for these diseases, but there are recommendations that vary with the individual characteristics of each patient. This article presents a comprehensive review of the literature, including an update on topics related to the diagnosis, follow-up, histopathological aspects and available treatments for lichen planopilaris and frontal fibrosing alopecia, highlighting their similarities, differences and peculiarities. (C) 2022 Sociedade Brasileira de Dermatologia. Published by Elsevier Espana, S.L.U.
引用
收藏
页码:348 / 357
页数:10
相关论文
共 50 条
  • [21] Prevalence estimates for lichen planopilaris and frontal fibrosing alopecia in the United States
    Trager, Megan H.
    Lavian, Jonathan
    Lee, Eunice Y.
    Gary, Dahsan
    Jenkins, Fabian
    Christiano, Angela M.
    Bordone, Lindsey A.
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2021, 85 (03) : AB8 - AB8
  • [22] Hair Loss in Lichen Planopilaris and Frontal Fibrosing Alopecia: Not Always Irreversible
    Batra, Prag
    Sukhdeo, Kumar
    Shapiro, Jerry
    SKIN APPENDAGE DISORDERS, 2020, 6 (02): : 125 - 129
  • [23] Efficacy and safety of JAK inhibitors in treating lichen planopilaris or frontal fibrosing alopecia
    Wang, Chaofan
    Jiang, Yiqun
    JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 2025,
  • [24] Frontal fibrosing alopecia and lichen planopilaris in HLA-identical mother and daughter
    Otero Rivas, Maria Mercedes
    Calleja Antolin, Sara
    Sanchez Sambucety, Pedro
    Samaniego Gonzalez, Elia
    Ruiz de Morales, Jose Maria Garcia
    Rodriguez Prieto, Manuel Angel
    INDIAN JOURNAL OF DERMATOLOGY VENEREOLOGY & LEPROLOGY, 2015, 81 (02): : 162 - 165
  • [25] Lichen Planopilaris and Frontal Fibrosing Alopecia as Model Epithelial Stem Cell Diseases
    Harries, Matthew J.
    Jimenez, Francisco
    Izeta, Ander
    Hardman, Jonathan
    Panicker, Sreejith Parameswara
    Poblet, Enrique
    Paus, Ralf
    TRENDS IN MOLECULAR MEDICINE, 2018, 24 (05) : 435 - 448
  • [26] The Prevalence of Type IV Hypersensitivity in Patients With Lichen Planopilaris and Frontal Fibrosing Alopecia
    Shtaynberger, Benjamin
    Bruder, Philip
    Zippin, Jonathan H.
    DERMATITIS, 2023, 34 (04) : 351 - 352
  • [27] The depth of inflammation in frontal fibrosing alopecia and lichen planopilaris: A potential distinguishing feature
    Wong, Denise
    Goldberg, Lynne J.
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2017, 76 (06) : 1183 - 1184
  • [28] Vitamin D deficiency among patients with lichen planopilaris or frontal fibrosing alopecia
    Ali, Shaheir
    Collins, Maya
    Wiss, Isabel Pupo
    Senna, Maryanne
    JAAD INTERNATIONAL, 2022, 8 : 109 - 110
  • [29] Evidence for neurogenic inflammation in lichen planopilaris and frontal fibrosing alopecia pathogenic mechanism
    Doche, Isabella
    Wilcox, George L.
    Ericson, Marna
    Valente, Neusa S.
    Romiti, Ricardo
    McAdams, Brian. D.
    Hordinsky, Maria K.
    EXPERIMENTAL DERMATOLOGY, 2020, 29 (03) : 282 - 285
  • [30] IDENTIFYING THE RELATIONSHIP BETWEEN THYROID DISEASE AND ALOPECIA AREATA, LICHEN PLANOPILARIS, AND FRONTAL FIBROSING ALOPECIA
    Nguyen, T. Q.
    Goh, C.
    JOURNAL OF INVESTIGATIVE MEDICINE, 2014, 62 (01) : 167 - 167