Lichen planopilaris and frontal fibrosing alopecia: review and update of diagnostic and therapeutic features

被引:25
|
作者
Costa Fechine, Carolina Oliveira [1 ]
Sakai Valente, Neusa Yuriko [1 ]
Romiti, Ricardo [1 ]
机构
[1] Univ Sao Paulo, Fac Med, Dept Dermatol, Sao Paulo, SP, Brazil
关键词
Alopecia; Diagnosis; Lichen planus; Review; Scalp dermatoses; Therapeutics; RETROSPECTIVE ANALYSIS; HYDROXYCHLOROQUINE; ISOTRETINOIN; EFFICACY; SCALP;
D O I
10.1016/j.abd.2021.08.008
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Lichen planopilaris and frontal fibrosing alopecia are primary scarring alopecias where diagnosis can be suggested by clinical and trichoscopy features, especially in the early stages, but scalp biopsy is the standard exam for definitive diagnosis. Frontal fibrosing alopecia is considered a variant of lichen planopilaris, as the histopathological findings are similar, with a perifollicular lymphohistiocytic infiltrate, sometimes with a lichenoid pattern. A thorough clinical examination, trichoscopy and photographic documentation are essential to assess the evolution and therapeutic response. To date, there are no validated treatments or guidelines for these diseases, but there are recommendations that vary with the individual characteristics of each patient. This article presents a comprehensive review of the literature, including an update on topics related to the diagnosis, follow-up, histopathological aspects and available treatments for lichen planopilaris and frontal fibrosing alopecia, highlighting their similarities, differences and peculiarities. (C) 2022 Sociedade Brasileira de Dermatologia. Published by Elsevier Espana, S.L.U.
引用
收藏
页码:348 / 357
页数:10
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