Superior Vena Cava Syndrome in Thoracic Malignancies

被引：66

作者：

Lepper, Philipp M. ^{[1
]}

Ott, Sebastian R. ^{[2
]}

Hoppe, Hanno ^{[3
]}

Schumann, Christian ^{[4
]}

Stammberger, Uz ^{[5
]}

Bugalho, Antonio ^{[6
]}

Frese, Steffen ^{[5
]}

Schmuecking, Michael ^{[7
]}

Blumstein, Norbert M. ^{[7
]}

Diehm, Nicolas ^{[8
]}

Bals, Robert ^{[1
]}

Hamacher, Juerg ^{[1
,2
,9
]}

机构：

[1] Univ Hosp Saarland, Dept Internal Med 5, D-66421 Homburg, Germany

[2] Univ Bern, Univ Spital Bern, Dept Pneumol, Bern, Switzerland

[3] Univ Bern, Univ Spital Bern, Dept Radiol, Bern, Switzerland

[4] Univ Hosp Ulm, Div Pulm Dis, Dept Internal Med, Ulm, Germany

[5] Univ Bern, Univ Spital Bern, Dept Thorac Surg, Bern, Switzerland

[6] Univ Nova Lisboa, Fac Ciencias Med, Dept Pneumol, Hosp Pulido Valente, P-1200 Lisbon, Portugal

[7] Univ Bern, Univ Spital Bern, Dept Radiat Therapy, Bern, Switzerland

[8] Univ Bern, Univ Spital Bern, Dept Clin & Intervent Angiol, Bern, Switzerland

[9] Lindenhofspital, Dept Pulm Med, Bern, Switzerland

来源：

RESPIRATORY CARE | 2011年 / 56卷 / 05期

关键词：

superior vena cava syndrome; small-cell lung cancer; SCLC; non-small-cell lung cancer; NSCLC; lymphoma; venous stenting; emergency external beam radiation therapy; glucocorticoids; CELL LUNG-CANCER; STAGE IIIA N2; PHASE-II; INDUCTION CHEMOTHERAPY; RADIATION-THERAPY; OBSTRUCTION; MANAGEMENT; RADIOTHERAPY; RESECTION; SURGERY;

D O I：

10.4187/respcare.00947

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

The superior vena cava syndrome (SVCS) comprises various symptoms due to occlusion of the SVC, which can be easily obstructed by pathological conditions (eg, lung cancer, due to the low internal venous pressure within rigid structures of the thorax [trachea, right bronchus, aorta]). The resulting increased venous pressure in the upper body may cause edema of the head, neck, and upper extremities, often associated with cyanosis, plethora, and distended subcutaneous vessels. Despite the often striking clinical presentation, SVCS itself is usually not a life-threatening condition. Currently, randomized controlled trials on many clinically important aspects of SVCS are lacking. This review gives an interdisciplinary overview of the pathophysiology, etiology, clinical manifestations, diagnosis, and treatment of malignant SVCS.

引用

页码：653 / 666

页数：14

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