Towards the Discovery of a Novel Class of Monoamine Oxidase Inhibitors: Structure-Property-Activity and Docking Studies on Chromone Amides

被引：37

作者：

Gaspar, Alexandra ^{[4
]}

Teixeira, Filipe ^{[1
]}

Uriarte, Eugenio ^{[2
]}

Milhazes, Nuno ^{[3
,4
]}

Melo, Andre ^{[1
]}

Cordeiro, M. Natalia D. S. ^{[1
]}

Ortuso, Francesco

Alcaro, Stefano

Borges, Fernanda ^{[4
]}

机构：

[1] Univ Porto, REQUIMTE, Dept Quim & Bioquim, Fac Ciencias, P-4169007 Oporto, Portugal

[2] Univ Santiago de Compostela, Dept Quim Organ, Fac Farm, Santiago De Compostela 15782, Spain

[3] Inst Super Ciencias Saude Norte, P-1317 R Cent De Gandra, Gandra Prd, Portugal

[4] Univ Porto, CIQUP, Dept Quim & Bioquim, Fac Ciencias, P-4169007 Oporto, Portugal

来源：

CHEMMEDCHEM | 2011年 / 6卷 / 04期

关键词：

chromone amides; conformational studies; molecular docking; monoamine oxidase inhibitors; NMR spectroscopy; ACCURATE DOCKING; AFFINITY; LIGANDS; GLIDE;

D O I：

10.1002/cmdc.201000452

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

[No abstract available]

引用

页码：628 / 632

页数：5

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