Noise enhances robustness of intracellular Ca2+ oscillations

被引：35
|
作者：
Perc, M [1 ]
Marhl, M [1 ]
机构：
[1] Univ Maribor, Fac Educ, Dept Phys, SI-2000 Maribor, Slovenia
来源：
PHYSICS LETTERS A | 2003年 / 316卷 / 05期
关键词：
robustness; flexibility; Gaussian noise; divergence; calcium oscillations;
D O I：
10.1016/j.physleta.2003.08.006
中图分类号：
O4 [物理学];
学科分类号：
0702 ;
摘要：
We investigate responses of a model for intracellular Ca2+ oscillations to external pulsatile forcing in the presence of additive Gaussian noise. Our results show that noise makes the system less susceptible to external forcing and thus enhances robustness of Ca2+ oscillations. The results can be well explained by the local divergence of limit cycles in the phase space. (C) 2003 Elsevier B.V. All rights reserved.
引用
收藏
页码：304 / 310
页数：7
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