Deep brain stimulation for phantom limb pain

被引:4
作者
Pang, David [1 ]
Ashkan, Keyoumars [2 ]
机构
[1] INPUT St Thomas Hosp, Pain Management Ctr, Consultant Pain Management, London SE1 7EH, England
[2] Kinss Coll Hosp NHS Fdn Trust, Dept Neurosurg, London, England
关键词
MOTOR CORTEX STIMULATION; SPINAL-CORD STIMULATION; ANTERIOR CINGULATE CORTEX; CHRONIC NEUROPATHIC PAIN; LONG-TERM; ELECTRICAL-STIMULATION; CORTICAL REORGANIZATION; AMPUTEES; SENSATIONS; AMPUTATION;
D O I
10.1016/j.ejpn.2022.05.009
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Phantom limb pain is a rare cause of chronic pain in children but it is associated with extremely refractory pain and disability. The reason for limb amputation is often due to treatment for cancer or trauma and it has a lower incidence compared to adults. The mechanism of why phantom pain exists remains uncertain and may be a result of cortical reorganisation as well as ectopic peripheral input. Treatment is aimed at reducing both symptoms as well as managing pain related disability and functional restoration. Neuromodulatory approaches using deep brain stimulation for phantom limb pain is reserved for only the most refractory cases. The targets for brain stimulation include the thalamic nuclei and motor cortex. Novel targets such as the anterior cingulate cortex remain experimental as cases of serious adverse effects such as seziures have limited their widespread uptake. A multidisciplinary approach is crucial to successful rehabilitation using a biopsychosocial pain management approach.
引用
收藏
页码:96 / 102
页数:7
相关论文
共 93 条
  • [1] Thalamic Deep Brain Stimulation for Neuropathic Pain: Efficacy at Three Years' Follow-Up
    Abreu, Vasco
    Vaz, Rui
    Rebelo, Virginia
    Rosas, Maria Jose
    Chamadoira, Clara
    Gillies, Martin J.
    Aziz, Tipu Z.
    Pereira, Erlick A. C.
    [J]. NEUROMODULATION, 2017, 20 (05): : 504 - 513
  • [2] Wireless Spinal Cord Stimulation Technology for the Treatment of Neuropathic Pain: A Single-Center Experience
    Ahmadi, Rezvan
    Hajiabadi, Mohammad Mehdi
    Unterberg, Andreas
    Geist, Christiane
    Campos, Benito
    [J]. NEUROMODULATION, 2021, 24 (03): : 591 - 595
  • [3] A survey of post-amputation pains in serving military personnel
    Aldington, Dominic
    Small, C.
    Edwards, D.
    Ralph, J.
    Woods, P.
    Jagdish, S.
    Moore, R. A.
    [J]. JOURNAL OF THE ROYAL ARMY MEDICAL CORPS, 2014, 160 (01) : 38 - 41
  • [4] Deep brain stimulation for phantom limb pain
    Bittar, RG
    Otero, S
    Carter, H
    Aziz, TZ
    [J]. JOURNAL OF CLINICAL NEUROSCIENCE, 2005, 12 (04) : 399 - 404
  • [5] Long-Term Results of Deep Brain Stimulation of the Anterior Cingulate Cortex for Neuropathic Pain
    Boccard, Sandra G. J.
    Prangnell, Simon J.
    Pycroft, Laurie
    Cheeran, Binith
    Moir, Liz
    Pereira, Erlick A. C.
    Fitzgerald, James J.
    Green, Alexander L.
    Aziz, Tipu Z.
    [J]. WORLD NEUROSURGERY, 2017, 106 : 625 - 637
  • [6] Long-term Outcomes of Deep Brain Stimulation for Neuropathic Pain
    Boccard, Sandra G. J.
    Pereira, Erlick A. C.
    Moir, Liz
    Aziz, Tipu Z.
    Green, Alexander L.
    [J]. NEUROSURGERY, 2013, 72 (02) : 221 - 230
  • [7] Noninvasive Brain Stimulation: Challenges and Opportunities for a New Clinical Specialty
    Boes, Aaron D.
    Kelly, Michael S.
    Trapp, Nicholas T.
    Stern, Adam P.
    Press, Daniel Z.
    Pascual-Leone, Alvaro
    [J]. JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES, 2018, 30 (03) : 173 - 179
  • [8] Factors associated with phantom limb pain: a 31/2-year prospective study
    Bosmans, Joline C.
    Geertzen, Jan H. B.
    Post, Wendy J.
    van der Schans, Cees P.
    Dijkstra, Pieter U.
    [J]. CLINICAL REHABILITATION, 2010, 24 (05) : 444 - 453
  • [9] Phantom Limb Pain in Young Cancer-related Amputees Recent Experience at St Jude Children's Research Hospital
    Burgoyne, Laura L.
    Billups, Catherine A.
    Jiron, Jose L., Jr.
    Kaddoum, Roland N.
    Wright, Becky B.
    Bikhazi, George B.
    Parish, Mary Edna
    Pereiras, Lilia A.
    [J]. CLINICAL JOURNAL OF PAIN, 2012, 28 (03) : 222 - 225
  • [10] CARLEN PL, 1978, NEUROLOGY, V28, P211, DOI 10.1212/WNL.28.3.211