Pulmonary Manifestations of Scleroderma and Mixed Connective Tissue Disease

被引：20

作者：

Hant, Faye N. ^{[1
]}

Herpel, Laura B. ^{[2
]}

Silver, Richard M. ^{[1
]}

机构：

[1] Med Univ S Carolina, Div Rheumatol & Immunol, Charleston, SC 29425 USA

[2] Med Univ S Carolina, Div Pulm Crit Care Allergy & Sleep Med, Charleston, SC 29425 USA

来源：

CLINICS IN CHEST MEDICINE | 2010年 / 31卷 / 03期

关键词：

Systemic sclerosis; Scleroderma; Interstitial lung disease; Mixed connective tissue disease; Pulmonary arterial hypertension; INTERSTITIAL LUNG-DISEASE; PROGRESSIVE SYSTEMIC-SCLEROSIS; SURFACTANT PROTEIN-D; HIGH-RESOLUTION CT; BRONCHOALVEOLAR LAVAGE FLUID; RIGHT-HEART CATHETERIZATION; STEM-CELL TRANSPLANTATION; GENETIC RISK-FACTOR; 6-MINUTE WALK TEST; ARTERIAL-HYPERTENSION;

D O I：

10.1016/j.ccm.2010.05.004

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Pulmonary manifestations are common in connective tissue diseases, and are associated with significant morbidity and mortality in this patient population. Systemic sclerosis (SSc) and mixed connective tissue disease (MCTD) are clinical entities for which the detection of lung involvement is essential to improve patient care and outcomes. This article discusses the pathogenesis, clinical presentation, and evaluation of the patient with pulmonary disease related to SSc and MCTD, with an emphasis on interstitial lung disease and pulmonary hypertension.

引用

页码：433 / +

页数：19

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