Prenylated p-Terphenyls from a Mangrove Endophytic Fungus, Aspergillus candidus LDJ-5

被引:30
作者
Zhou, Guoliang [1 ]
Chen, Xiaohui [1 ]
Zhang, Xiaomin [1 ]
Che, Qian [1 ]
Zhang, Guojian [1 ,2 ]
Zhu, Tianjiao [1 ]
Gu, Qianqun [1 ]
Li, Dehai [1 ,2 ]
机构
[1] Ocean Univ China, Qingdao, Peoples R China
[2] Pilot Natl Lab Marine Sci & Technol, Qingdao, Peoples R China
来源
JOURNAL OF NATURAL PRODUCTS | 2020年 / 83卷 / 01期
基金
中国博士后科学基金;
关键词
METABOLITES; DERIVATIVES; SCLEROTIA;
D O I
10.1021/acs.jnatprod.9b00004
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Nine previously undescribed prenylated p-terphenyls, prenylterphenyllins F-J (1, 2, 4-6) and prenylcandidusins D-G (3, 7-9), were isolated from an endophytic fungus, Aspergillus candidus LDJ-5. Their structures were determined from NMR and MS data. Differing from previously reported p-terphenyls, compound 3 represents a rare 6,5,6,6-fused ring system. Compounds 4-6 are antimicrobial, and compounds 1, 4, 6, and 9 are cytotoxic.
引用
收藏
页码:8 / 13
页数:6
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