Risk factor panels associated with hypertension in obstructive sleep apnea patients with different body mass indexes

被引:3
|
作者
Hu, Wei [1 ]
Jin, Xian [1 ]
Gu, Jun [1 ]
Zhang, Peng [1 ]
Yu, Qiang [1 ]
Yin, Guizhi [1 ]
Lu, Yi [1 ]
Xiao, Hongbing [1 ]
Chen, Yueguang [1 ]
Zhang, Dadong [1 ]
机构
[1] Ctr Hosp Minhang Dist, Dept Cardiol, Shanghai 201199, Peoples R China
关键词
Body mass indexes; hypertension; obstructive sleep apnea; risk factor panels; CARDIOVASCULAR CONSEQUENCES; SYMPATHETIC ACTIVATION; VISCERAL OBESITY; URIC-ACID; MECHANISMS; DISEASE; POPULATION; PRESSURE; SYSTEM;
D O I
10.1016/j.jash.2015.01.015
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
Although hypertension (HTN), obstructive sleep apnea (USA), and obesity frequently co-occur, the precise role of obesity in this interrelationship is not completely understood. A total of 727 USA patients were assigned to body mass index (BMI) <25 (27.6%; n = 201), 25 <= BMI <29.99 (53.4%; n = 388), and BMI >= 30 (19%; n = 138). HTN risk factors in each group were evaluated. A total of 244 (33.6%) patients exhibited co-morbid HTN, of whom 20.5% (50/244), 52.9% (129/244), and 26.6% (65/244) were distributed between the BMI <25, 25 <= BMI <29.99, and BMI >= 30 groups, respectively. Multiple logistic regression indicated that age, male gender, triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), and apnea-hypopnea index (AHI) scores were HTN risk factors for the BMI<25 group. In the 25 <= BMI <29.99 group, risk factors were age, BMI, diabetes, and AHI. Finally, in the BMI >= 30 group, risk factors were age, diabetes, TG, LDL-C and AHI. These results demonstrate that different risk factor panels were associated with HTN in USA patients with different BMIs. 2015 American Society of Hypertension. All rights reserved.
引用
收藏
页码:382 / 389
页数:8
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