Prevalence Rate of Exercise-Induced Bronchoconstriction in Annaba (Algeria) Schoolchildren

被引:26
作者
Benarab-Boucherit, Yasmina [2 ]
Mehdioui, Hacene
Nedjar, Faycal [3 ]
Delpierre, Stephane [1 ]
Bouchair, Nadira [4 ]
Aberkane, Abdelhamid [5 ]
机构
[1] Fac Med Nord, IFR Jean Roche, Physiol & Physiopathol Condit Oxygenat Extremes P, UMR MD2, F-13005 Marseille, France
[2] CHU Ibn Rochd, Serv Physiol & Explorat Fonct, Annaba 23000, Algeria
[3] CHU Ibn Badis, Serv Physiol & Explorat Fonct, Unite DHLA, Constantine 25000, Algeria
[4] Clin St Therese, Serv Pediat, Annaba 23000, Algeria
[5] CHU Ibn Badis, Serv Reanimat Med, Constantine 25000, Algeria
关键词
air pollution; children; exercise-induced bronchoconstriction; free running; peak expiratory flow; ENVIRONMENTAL TOBACCO-SMOKE; INDUCED BRONCHOSPASM; AIRWAY INFLAMMATION; ASTHMA; HYPERPNEA; BIRTH;
D O I
10.3109/02770903.2011.578315
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Background. We studied the prevalence rate of exercise-induced bronchoconstriction (EIB) in Annaba schoolchildren. No previous assessment of this syndrome had ever been done in Algeria. Methods. EIB was evaluated using the 6 min free running test (6MFRT) on 286 children, 87.4% of whom were 10-12 years old. They performed the test in the morning, during the autumn-winter season. Peak expiratory flow rate (PEFR) was measured before, and then 5 and 10 min after the 6MFRT, a 15% or more decrease in post-exercise PEFR being defined as significant. Results. EIB was much more frequent in asthmatic than in nonasthmatic children (47.0% vs. 13.9%, p < .001) and the drop in PEFR was more marked among the former. EIB was observed more often in a cool temperature (<8 degrees C). There were relatively more children who were either eutrophic or overweight among those presenting an EIB. Past histories of nocturnal wheezing and rhinoconjunctivitis presented respectively the best specificity (96.7%) and sensitivity (84.8%). Children of unemployed workers presented the highest occurrence of EIB. Passive smoking appeared as the only factor being related to EIB among the indoor pollutants. The prevalence rate of asthma (6.7%) was higher than in a previous cross-sectional epidemiological survey study performed in the Maghreb. The prevalence rate of EIB (13.9%) was situated in the upper range of the results given worldwide. Conclusions. These features of a fairly high bronchial hyperresponsiveness could be facilitated by the polluted environment of the city.
引用
收藏
页码:511 / 516
页数:6
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