Statins, ventricular arrhythmias and heart rate variability in patients with implantable cardioverter defibrillators and coronary heart disease

被引:15
|
作者
Riahi, S
Schmidt, EB
Christensen, JH
Heath, F
Pedersen, AK
Nielsen, JC
Molgaard, H
Toft, E
机构
[1] Arhus Univ Hosp, Aalborg Hosp, Dept Cardiol, DK-9100 Aalborg, Denmark
[2] Arhus Univ Hosp, Aalborg Hosp, Cardiovasc Res Ctr, Aalborg, Denmark
[3] Arhus Univ Hosp, Aalborg Hosp, Dept Nephrol, Aalborg, Denmark
[4] Aalborg Univ, Dept Hlth Sci & Technol, Ctr Sensory Motor Interact, Aalborg, Denmark
[5] Arhus Univ Hosp, Dept Cardiol, Skejby Hosp, Aarhus, Denmark
关键词
heart rate variability; implanted cardioverter defibrillator; HMG-CoA reductase inhibitors; coronary heart disease; plasma lipids;
D O I
10.1159/000088175
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The aim of this study was to evaluate whether the incidence of ventricular arrhythmias and heart rate variability were infl uenced by statin treatment and lipid levels in patients treated with an implantable cardioverter defibrillator (ICD). Heart rate variability measurements were performed in 86 patients with coronary heart disease and an ICD implant. The number of events with ventricular fibrillation and ventricular tachycardia were recorded during a 12-month period. This study lends little support for an antiarrhythmic effect of statins or any relation between plasma lipids and lipoproteins and malignant ventricular arrhythmias in patients with an ICD.
引用
收藏
页码:210 / 214
页数:5
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