Benefit of Gluten-Free Diet in Idiopathic Pulmonary Hemosiderosis in Association With Celiac Disease

被引:30
作者
Sethi, Gulshan R. [2 ]
Singhal, Kamal K. [2 ]
Puri, Amarender S. [1 ]
Mantan, Mukta [2 ]
机构
[1] GB Pant Hosp, Dept Gastroenterol, New Delhi 110002, India
[2] Lok Nayak Hosp, Dept Pediat, New Delhi, India
关键词
Lane-Hamilton syndrome; celiac disease; idiopathic pulmonary hemosiderosis; gluten-free diet; FOLLOW-UP;
D O I
10.1002/ppul.21357
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Lane-Hamilton syndrome refers to the uncommon co-occurrence of idiopathic pulmonary hemosiderosis and celiac disease (CD). Three children aged between 7 and 14 years with IPH were detected to have co-existing non-diarrheal CD. Institution of gluten-free diet in each of the three children resulted in amelioration of the pulmonary symptoms along with improvement of anthropometric parameters and hemoglobin over a short-term follow-up period of 8-17 months. Inhaled/oral steroids and immunosuppressants could be weaned off after dietary exclusion therapy in each of the three children. Gluten free diet should be instituted in all patients diagnosed with Lane-Hamilton syndrome. It ameliorates both the pulmonary as well as the intestinal symptoms although the precise mechanism of the pulmonary response is as yet unclear. Pediatr Pulmonol. 2011; 46: 302-305. (C) 2010 Wiley-Liss, Inc.
引用
收藏
页码:302 / 305
页数:4
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