Insight into the pathogenesis and nature of Central giant cell lesions of the jaws

被引:9
作者
Edwards, Paul-Charles [1 ,2 ]
机构
[1] Indiana Univ, Sch Dent, Amer Board Oral & Maxillofacial Pathol, Indianapolis, IN 46202 USA
[2] Indiana Univ, Sch Dent, Dept Oral Pathol, Indianapolis, IN 46202 USA
来源
MEDICINA ORAL PATOLOGIA ORAL Y CIRUGIA BUCAL | 2015年 / 20卷 / 02期
关键词
Central giant cell lesion; RASopathy; CENTRAL ODONTOGENIC FIBROMA; NOONAN-SYNDROME; GRANULOMAS; CHERUBISM; MUTATIONS; TUMORS; BONE; GENE; SH3BP2; H3F3A;
D O I
10.4317/medoral.20499
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Central giant cell lesions of the jaws are not uncommon. While the majority of these represent single, sporadic lesions, histologically identical lesions are seen in association with a number of other bone lesions, as well as in certain syndromes. This manuscript offers a brief update on recent developments in this area that provide new insight into the pathogenesis and nature of Central Giant Cell Lesions of the Jaws.
引用
收藏
页码:E196 / E198
页数:3
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