Detection Methods of Human and Animal Influenza Virus-Current Trends

被引:67
作者
Dziabowska, Karolina [1 ,2 ]
Czaczyk, Elzbieta [1 ,2 ]
Nidzworski, Dawid [1 ,2 ]
机构
[1] Inst Biotechnol & Mol Med, 3 Trzy Lipy St, PL-80172 Gdansk, Poland
[2] SensDx SA, 14b Postepu St, PL-02676 Warsaw, Poland
来源
BIOSENSORS-BASEL | 2018年 / 8卷 / 04期
关键词
influenza virus; Rapid Influenza Diagnostic Tests RIDTs; electrochemical detection; optical detection; ELISA; PCR; MEDIATED ISOTHERMAL AMPLIFICATION; RAPID DIAGNOSTIC-TESTS; A VIRUS; ELECTROCHEMICAL IMMUNOSENSOR; ULTRASENSITIVE DETECTION; GRAPHENE OXIDE; GOLD NANOPARTICLES; B VIRUSES; ASSAY; BIOSENSOR;
D O I
10.3390/bios8040094
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
The basic affairs connected to the influenza virus were reviewed in the article, highlighting the newest trends in its diagnostic methods. Awareness of the threat of influenza arises from its ability to spread and cause a pandemic. The undiagnosed and untreated viral infection can have a fatal effect on humans. Thus, the early detection seems pivotal for an accurate treatment, when vaccines and other contemporary prevention methods are not faultless. Public health is being attacked with influenza containing new genes from a genetic assortment between animals and humankind. Unfortunately, the population does not have immunity for mutant genes and is attacked in every viral outbreak season. For these reasons, fast and accurate devices are in high demand. As currently used methods like Rapid Influenza Diagnostic Tests lack specificity, time and cost-savings, new methods are being developed. In the article, various novel detection methods, such as electrical and optical were compared. Different viral elements used as detection targets and analysis parameters, such as sensitivity and specificity, were presented and discussed.
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页数:24
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