Investigation into Polymorphism of Lamivudine Using Terahertz Time-domain Spectroscopy

被引：0
|
作者：
Qin, Dan [1 ]
Zhang, Huili [1 ]
Hong, Zhi [1 ]
Du, Yong [1 ]
机构：
[1] China Jiliang Univ, Ctr THz Res, Hangzhou 310018, Zhejiang, Peoples R China
来源：
2018 43RD INTERNATIONAL CONFERENCE ON INFRARED, MILLIMETER, AND TERAHERTZ WAVES (IRMMW-THZ) | 2018年
关键词：
TRANSFORMATION; FAMOTIDINE;
D O I：
暂无
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
Terahertz absorption spectra were obtained for hydrated and anhydrous polymorphic forms of lamivudine. The results show that the interaction between crystalline water and lamivudine molecule has an important effect on the vibration modes of lamivudine polymorphs. The differences in the terahertz spectra were correlated with the corresponding structures and shown to be mainly due to the inter-molecular interactions effect.
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页数：2
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